Your browser doesn't support javascript.
COVID-19 associated myelitis: A case series
Medical Journal of Dr. D.Y. Patil Vidyapeeth ; 15(7):S106-S109, 2022.
Article in English | Scopus | ID: covidwho-2024832
ABSTRACT
Spinal cord involvement in COVID-19 infections can be varied and may present as acute transverse myelitis, acute necrotizing myelitis, neuromyelitis optica spectrum disorder, Myelin oligodendrocyte-associated glycoprotein (MOG) antibody myelitis, and SARS-CoV-2 myelitis. We retrospectively analyzed eight cases of COVID-19-associated myelitis. All patients had only mild antecedent symptoms of COVID-19 infection and were admitted with clinical features of acute transverse myelitis confirmed on neuroimaging. Seven patients had longitudinally extensive transverse myelitis (LETM). Serum Aquaporin-4 antibodies (NMO), cerebrospinal fluid (CSF) oligoclonal bands, and RT PCR for COVID-19 were negative. Serum MOG antibodies were positive in three patients;out of this two had CSF pleocytosis. All patients were treated with steroids followed by plasmapheresis. Five cases showed good improvement (increase in power by grade 2 or more), while three cases that were MOG positive had poor outcomes with either minimal or no improvement. The severity of COVID-19 infection was not related to the development of myelitis. Seven cases had LETM. Response to therapy was not uniform and the presence of MOG antibodies and CSF pleocytosis was associated with poor outcomes. © Medical Journal of Dr. D.Y. Patil Vidyapeeth 2022.
Keywords

Full text: Available Collection: Databases of international organizations Database: Scopus Language: English Journal: Medical Journal of Dr. D.Y. Patil Vidyapeeth Year: 2022 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: Databases of international organizations Database: Scopus Language: English Journal: Medical Journal of Dr. D.Y. Patil Vidyapeeth Year: 2022 Document Type: Article