Presence of SARS-CoV-2 in human tears detected by quantitative real time PCR (qRT-PCR)
Medical Journal of Dr. D.Y. Patil Vidyapeeth
; 15(7):S46-S48, 2022.
Article
in English
| Scopus | ID: covidwho-2024851
ABSTRACT
Background:
COVID-19 has caused a pandemic since the end of the year 2019. Controversy regarding the presence of the SARS-CoV-2 in tears and conjunctival sac has created suspense throughout. Moderate to severe dry eye has been observed in the patients infected with COVID-19. Material andMethod:
We conducted a descriptive, prospective observational study. We enrolled 16 patients fulfilling the inclusion criteria for our study. Patients affected with acute COVID-19 from 28-9-2020 to 9-10-2020 registered at our hospital and willing to participate were included. Tears and conjunctival swabs were taken at the interval of 24 h;consecutively three samples were taken from one COVID-19 infected patient. In total, 48 samples were analyzed by qRT-PCR.Result:
We had 16 participants, 47% were females and 53% were males;2/16 [12.5%] patients showed the presence of SARS-CoV-2 in tears and conjunctival swabs. Both the infected patients were females, and they did not have any obvious abnormal ocular conditions. Schirmer strip reading, however, showed a severe dry eye in both the patients.Conclusion:
We identified dry eye ranging from mild to moderate to severe [Schirmer 1 reading ranged from 2 to 8 mm] in all our patients admitted to the COVID-19 ward. The SARS-CoV-2 gene seems to be mutating. More work needs to be done to find the viral load in the tears and any abnormalities in the eyes accordingly. © Medical Journal of Dr. D.Y. Patil Vidyapeeth 2022.
Full text:
Available
Collection:
Databases of international organizations
Database:
Scopus
Language:
English
Journal:
Medical Journal of Dr. D.Y. Patil Vidyapeeth
Year:
2022
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS