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Genome characterization and potential risk assessment of the novel SARS-CoV-2 variant Omicron (B.1.1.529)
Zoonoses ; 1(13), 2021.
Article in English | CAB Abstracts | ID: covidwho-2025746
ABSTRACT
As the novel coronavirus SARS-CoV-2 spread around the world, multiple waves of variants emerged, thus leading to local or global population shifts during the pandemic. A new variant named Omicron (PANGO lineage B.1.1.529), which was first discovered in southern Africa, has recently been proposed by the World Health Organization to be a Variant of Concern. This variant carries an unusually large number of mutations, particularly on the spike protein and receptor binding domain, in contrast to other known major variants. Some mutation sites are associated with enhanced viral transmission, infectivity, and pathogenicity, thus enabling the virus to evade the immune protective barrier. Given that the emergence of the Omicron variant was accompanied by a sharp increase in infection cases in South Africa, the variant has the potential to trigger a new global epidemic peak. Therefore, continual attention and a rapid response are required to decrease the possible risks to public health.
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Full text: Available Collection: Databases of international organizations Database: CAB Abstracts Type of study: Prognostic study Topics: Variants Language: English Journal: Zoonoses Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: CAB Abstracts Type of study: Prognostic study Topics: Variants Language: English Journal: Zoonoses Year: 2021 Document Type: Article