Advances in spectral techniques for detection of pathogenic microorganisms
Zoonoses
; 2(8), 2022.
Article
in English
| CAB Abstracts | ID: covidwho-2025747
ABSTRACT
The highly contagious viral illness Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus-2, has led to nearly 5 million deaths worldwide. The detection of highly infectious pathogens or novel pathogens causing emerging infectious diseases is highly challenging. Encouragingly, spectral detection-including laser-induced fluorescence spectroscopy, infrared absorption spectroscopy, Raman spectroscopy and their combinations-has been broadly used to detect pathogenic microorganisms on the basis of their physical and chemical characteristics. Surface-enhanced Raman spectroscopy with labels can detect organisms at a minimum concentration of 3 cells/mL. The changes in cells' biochemical reactions before and after polioviral infection can be detected by Fourier transform infrared spectroscopy. However, the sensitivity and specificity of different spectral detection categories differs, owing to their different detection principles. Flexible detection methods require interdisciplinary researchers familiar with both pathogen biology and instruments. This review summarizes the advances in spectral techniques used in detecting pathogenic microorganism.
Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210]; Techniques and Methodology [ZZ900]; analytical methods; coronavirus disease 2019; detection; fluorescence; infrared spectroscopy; laser fluorescence spectroscopy; pathogens; Raman spectroscopy; reviews; spectral analysis; spectroscopy; viral diseases; Severe acute respiratory syndrome coronavirus 2; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; analytical techniques; SARS-CoV-2; viral infections
Full text:
Available
Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
English
Journal:
Zoonoses
Year:
2022
Document Type:
Article
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