New-onset systemic lupus erythematosus following BNT162b2 mRNA COVID-19 vaccine: a case series and literature review.
Rheumatol Int
; 42(12): 2261-2266, 2022 12.
Article
in English
| MEDLINE | ID: covidwho-2027476
ABSTRACT
Emerging data evaluated the possible link between the Coronavirus 19 (COVID-19) vaccine and acute flares of rheumatic autoimmune diseases. However, the association between the COVID-19 vaccine and the development of de-novo rheumatic autoimmune diseases remained unclear. We report the first case series of three male patients who developed new-onset systemic lupus erythematosus following receiving Pfizer BNT162b2 mRNA vaccination. The clinical characteristics share some similarities with drug-induced lupus. More patients with SLE following COVID-19 may be diagnosed in the future. Additional studies will provide more significant insights into the possible immunogenic influence of the COVID-19 vaccine.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Autoimmune Diseases
/
COVID-19 Vaccines
/
COVID-19
/
Lupus Erythematosus, Systemic
Type of study:
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Reviews
Topics:
Vaccines
Limits:
Humans
/
Male
Language:
English
Journal:
Rheumatol Int
Year:
2022
Document Type:
Article
Affiliation country:
S00296-022-05203-3
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