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Assessment of a novel, easy-to-implement, aerosolized H2O2 decontamination method for single-use filtering facepiece respirators in case of shortage.
Novák, Martin; Gloor, Christian; Wicki, Esther; Herb, Dorothea; Schibli, Adrian; Richner, Gilles.
  • Novák M; Research and Strategic Business Development, SKAN AG, Allschwil, Switzerland.
  • Gloor C; Federal Office for Civil Protection, Spiez Laboratory, Spiez, Switzerland.
  • Wicki E; Division of Infectious Diseases and Hospital Epidemiology, Zurich City Hospital, Zurich, Switzerland.
  • Herb D; Division of Infectious Diseases and Hospital Epidemiology, Zurich City Hospital, Zurich, Switzerland.
  • Schibli A; Division of Infectious Diseases and Hospital Epidemiology, Zurich City Hospital, Zurich, Switzerland.
  • Richner G; Federal Office for Civil Protection, Spiez Laboratory, Spiez, Switzerland.
J Occup Environ Hyg ; 19(10-11): 663-675, 2022.
Article in English | MEDLINE | ID: covidwho-2028921
ABSTRACT
The COVID-19 pandemic has affected the world and caused a supply shortage of personal protection equipment, especially filtering facepiece respirators (FFP). This has increased the risk of many healthcare workers contracting SARS-CoV-2. Various strategies have been assessed to tackle these supply issues. In critical shortage scenarios, reusing single-use-designed respirators may be required. Thus, an easily applicable and reliable FFP2 (or alike) respirator decontamination method, allowing safe re-use of FFP2 respirators by healthcare personnel, has been developed and is presented in this study. A potent and gentle aerosolized hydrogen peroxide (12% wt) method was applied over 4 hr to decontaminate various brands of FFP2 respirators within a small common room, followed by adequate aeration and storage overnight. The microbial efficacy was tested on unused respirator pieces using spores of Geobacillus stearothermophilus. Further, decontamination effectiveness was tested on used respirators after one 12-hr shift by swabbing before and after the decontamination. The effects of up to ten decontamination cycles on the respirators' functionality were evaluated using material properties, the structural integrity of the respirators, and fit tests with subjects. The suggested H2O2 decontamination procedure was proven to be (a) sufficiently potent (no microbial recovery, total inactivation of biological indicators as well as spore inoculum on critical respirator surfaces), (b) gentle as no significant damage to the respirator structural integrity and acceptable fit factors were observed, and (c) safe as no H2O2 residue were detected after the defined aeration and storage. Thus, this easy-to-implement and scalable method could overcome another severe respirator shortage, providing enough flexibility to draft safe, effective, and logistically simple crisis plans. However, as highlighted in this study, due to the wealth of design and material used in different models and brands of respirators, the decontamination process should be validated for each FFP respirator model before its field implementation.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Limits: Humans Language: English Journal: J Occup Environ Hyg Journal subject: Occupational Medicine / Environmental Health Year: 2022 Document Type: Article Affiliation country: 15459624.2022.2125519

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study Limits: Humans Language: English Journal: J Occup Environ Hyg Journal subject: Occupational Medicine / Environmental Health Year: 2022 Document Type: Article Affiliation country: 15459624.2022.2125519