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Factors Associated With COVID-19 Breakthrough Infections in Large Midwestern Healthcare System: Implications for Vulnerable Healthcare Personnel.
Rivelli, Anne; Fitzpatrick, Veronica; Copeland, Kenneth; Richards, Jon.
  • Rivelli A; From the Advocate Aurora Health, Downers Grove, Illinois (Rivelli, Fitzpatrick, Copeland, Richards); Advocate Aurora Research Institute, Milwaukee, Wisconsin (Rivelli, Fitzpatrick); and ACL Laboratories, Milwaukee, Wisconsin (Copeland).
J Occup Environ Med ; 64(8): 635-641, 2022 08 01.
Article in English | MEDLINE | ID: covidwho-2029126
ABSTRACT

OBJECTIVE:

The aim of the study is to identify factors associated with breakthrough infection among a cohort of Midwestern healthcare personnel (HCP).

METHODS:

SARS-CoV-2-positive test results between March 1, 2020, and July 31, 2021, were collected from electronic medical records of HCP to identify breakthrough infections.

RESULTS:

Healthcare personnel who were younger than 35 years, received the Pfizer vaccine, and worked in COVID clinical units had greater adjusted odds of breakthrough infection. COVID infection before full vaccination was associated with reduced odds of breakthrough infection.

CONCLUSIONS:

Our study concluded that the most vulnerable HCP are younger, working in COVID-19 clinical units, and received Pfizer-BioNTech primary series vaccines. Healthcare personnel who had COVID before vaccination were at reduced risk of breakthrough infection, indicating that supplemental immunity could better protect at-risk HCP groups.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: J Occup Environ Med Journal subject: Occupational Medicine / Environmental Health Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: J Occup Environ Med Journal subject: Occupational Medicine / Environmental Health Year: 2022 Document Type: Article