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Urticaria relapse after mRNA COVID-19 vaccines in patients affected by chronic spontaneous urticaria and treated with antihistamines plus omalizumab: A single-center experience.
Picone, Vincenzo; Napolitano, Maddalena; Martora, Fabrizio; Guerriero, Luigi; Fabbrocini, Gabriella; Patruno, Cataldo.
  • Picone V; Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
  • Napolitano M; Department of Medicine and Health Sciences Vincenzo Tiberio, University of Molise, Campobasso, Italy.
  • Martora F; Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
  • Guerriero L; Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
  • Fabbrocini G; Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
  • Patruno C; Department of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Dermatol Ther ; 35(11): e15838, 2022 Nov.
Article in English | MEDLINE | ID: covidwho-2029319
ABSTRACT
Urticaria is a disease characterized by wheals and/or angioedema. Chronic spontaneous urticaria (CSU) occurs for longer than 6 weeks and appears independently of any identifiable exogenous stimulus. During the vaccination campaign for Coronavirus disease 2019 (COVID-19) pandemic, several cutaneous adverse events have been described, among which urticaria lasting less than 6 weeks (acute urticaria, AU). AU due to vaccines can be IgE or non-IgE mediated; the former typically develop within 4 h of drug exposure, the latter occurs later and the mechanism is unclear. In this retrospective study we analyzed the frequency and clinical characteristics of urticaria occurring after COVID-19 vaccine (post-vaccination urticaria relapse) in adult CSU patients treated with antihistamine and omalizumab, and in clinical remission.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Urticaria / Anti-Allergic Agents / Chronic Urticaria / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines Limits: Adult / Humans Language: English Journal: Dermatol Ther Journal subject: Dermatology Year: 2022 Document Type: Article Affiliation country: Dth.15838

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Urticaria / Anti-Allergic Agents / Chronic Urticaria / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines Limits: Adult / Humans Language: English Journal: Dermatol Ther Journal subject: Dermatology Year: 2022 Document Type: Article Affiliation country: Dth.15838