HAEMATOLOGICAL AND COAGULATION PROFILE IN PEDIATRIC PATIENTS WITH COVID 19

ABSTRACT

Background:COVID 19caused by severe acute respiratory syndrome corona virus2(SARS Cov2) involves respiratory and other systems. Patient with Covid 19 presents with wide range of hematological and coagulation abnormalities. Hemostatic abnormalities in Covid 19 are related with disease progression, severity and mortality. The objective of our study is to evaluate the role of hematological and coagulation parameters in determination of Covid 19 severity.Materials and methods: Total 70 cases were enrolled in the study, conducted in department of pathology at Bangalore Medical college and research institute, Bangalore. Hematological and coagulation parameters were compared with mild, moderate, severe and critical. Appropriate statistical analysis is applied.Result: Parameters like WBC, Neutrophils, HCT,NLR were higher in patients with severe disease when compared to mild and moderate cases.PT, D-Dimer did not show statistically significant association with severity of disease.Conclusion: The study concluded that leukocytosis, neutrophilia,elevated NLR are associated with severity of the disease