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Exercise effects on cardiovascular disease: from basic aspects to clinical evidence.
Sanchis-Gomar, Fabian; Lavie, Carl J; Marín, Jorge; Perez-Quilis, Carme; Eijsvogels, Thijs M H; O'Keefe, James H; Perez, Marco V; Blair, Steven N.
  • Sanchis-Gomar F; Department of Physiology, Faculty of Medicine, University of Valencia, Avda. Blasco Ibáñez 15, 46001, Valencia, Spain.
  • Lavie CJ; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, 300 Pasteur Dr, MC 5773, Stanford, CA, 94305, USA.
  • Marín J; John Ochsner Heart and Vascular Institute, Ochsner Clinical School, The University of Queensland School of Medicine, 1514 Jefferson Highway New Orleans, LA 70121, USA.
  • Perez-Quilis C; Department of Physiatry and Nursing, GENUD (Growth, Exercise, NUtrition and Development) Research Group, Faculty of Health Sciences, University of Zaragoza, Calle Domingo Miral, s/n, 50009 Zaragoza, Spain.
  • Eijsvogels TMH; Department of Physiology, Faculty of Medicine, University of Valencia, Avda. Blasco Ibáñez 15, 46001, Valencia, Spain.
  • O'Keefe JH; Department of Physiology, Radboud Institute for Health Science, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Perez MV; St. Luke's Mid America Heart Institute, University of Missouri, Kansas City, MO 64111, USA.
  • Blair SN; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, 300 Pasteur Dr, MC 5773, Stanford, CA, 94305, USA.
Cardiovasc Res ; 118(10): 2253-2266, 2022 Jul 27.
Article in English | MEDLINE | ID: covidwho-2032022
ABSTRACT
Cardiovascular (CV) disease (CVD) remains the leading cause of major morbidity and CVD- and all-cause mortality in most of the world. It is now clear that regular physical activity (PA) and exercise training (ET) induces a wide range of direct and indirect physiologic adaptations and pleiotropic benefits for human general and CV health. Generally, higher levels of PA, ET, and cardiorespiratory fitness (CRF) are correlated with reduced risk of CVD, including myocardial infarction, CVD-related death, and all-cause mortality. Although exact details regarding the ideal doses of ET, including resistance and, especially, aerobic ET, as well as the potential adverse effects of extreme levels of ET, continue to be investigated, there is no question that most of the world's population have insufficient levels of PA/ET, and many also have lower than ideal levels of CRF. Therefore, assessment and promotion of PA, ET, and efforts to improve levels of CRF should be integrated into all health professionals' practices worldwide. In this state-of-the-art review, we discuss the exercise effects on many areas related to CVD, from basic aspects to clinical practice.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / Cardiorespiratory Fitness Type of study: Diagnostic study / Experimental Studies / Prognostic study Limits: Humans Language: English Journal: Cardiovasc Res Year: 2022 Document Type: Article Affiliation country: Cvr

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / Cardiorespiratory Fitness Type of study: Diagnostic study / Experimental Studies / Prognostic study Limits: Humans Language: English Journal: Cardiovasc Res Year: 2022 Document Type: Article Affiliation country: Cvr