Molecular characterization of Infectious bronchitis virus in Southwestern China for the protective efficacy evaluation of four live vaccine strains
Zhongguo Yufang Shouyi Xuebao / Chinese Journal of Preventive Veterinary Medicine
; 44(1):108-108, 2022.
Article
in English, Chinese
| CAB Abstracts | ID: covidwho-2034138
ABSTRACT
Avian infectious bronchitis (IB) is one of the acute and highly contagious upper respiratory tract infectious diseases in poultry caused by the Infectious bronchitis virus (IBV), which significantly affects the health and development of world poultry farming industry. IBV RNA polymerase lacks a complete correctional function and is prone to gene mutation and RNA-RNA recombination during the replication process, resulting in the emergence of new serotypes, genotypes and mutant strains. The continuous generation of recombinant strains through homologous recombination between strains also complicates the prevention and control of IB. Therefore, monitoring the genetic evolutionary characteristics of circulating strains and evaluating the protective effect of commonly used vaccines against local circulating strains of IBV are the keys to preventing and controlling this disease.
Prion, Viral, Bacterial and Fungal Pathogens of Animals [LL821]; Genetics and Molecular Biology of Microorganisms [ZZ395]; Animal Immunology [LL650]; Host Resistance and Immunity [HH600]; Molecular Biology and Molecular Genetics [ZZ360]; Taxonomy and Evolution [ZZ380]; strains; disease prevention; bronchitis; disease control; lungs; respiratory diseases; genes; mutations; homologous recombination; vaccines; molecular genetics; characterization; efficacy; avian infectious bronchitis; Infectious bronchitis virus; China; Avian coronavirus; Gammacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; APEC countries; East Asia; Asia; high Human Development Index countries; upper-middle income countries; IBV infection; People's Republic of China; lung diseases; biochemical genetics
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Collection:
Databases of international organizations
Database:
CAB Abstracts
Type of study:
Experimental Studies
Topics:
Vaccines
Language:
English
/
Chinese
Journal:
Chinese Journal of Preventive Veterinary Medicine
Year:
2022
Document Type:
Article
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