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Trajectories of common mental disorders symptoms before and during the COVID-19 pandemic: findings from the ELSA-Brasil COVID-19 Mental Health Cohort.
Fatori, Daniel; Suen, Paulo; Bacchi, Pedro; Afonso, Leonardo; Klein, Izio; Cavendish, Beatriz A; Lee, Younga H; Liu, Zhaowen; Bauermeister, Joshua; Moreno, Marina L; Viana, Maria Carmen; Goulart, Alessandra C; Santos, Itamar S; Bauermeister, Sarah; Smoller, Jordan; Lotufo, Paulo; Benseñor, Isabela M; Brunoni, André R.
  • Fatori D; Faculdade de Medicina da, Universidade de São Paulo, R. Dr. Ovídio Pires de Campos, 785-Cerqueira César, CEAPESQ, Sala 9, São Paulo, SP, 05403-903, Brazil. daniel.fatori@gmail.com.
  • Suen P; Faculdade de Medicina da, Universidade de São Paulo, R. Dr. Ovídio Pires de Campos, 785-Cerqueira César, CEAPESQ, Sala 9, São Paulo, SP, 05403-903, Brazil.
  • Bacchi P; Faculdade de Medicina da, Universidade de São Paulo, R. Dr. Ovídio Pires de Campos, 785-Cerqueira César, CEAPESQ, Sala 9, São Paulo, SP, 05403-903, Brazil.
  • Afonso L; Faculdade de Medicina da, Universidade de São Paulo, R. Dr. Ovídio Pires de Campos, 785-Cerqueira César, CEAPESQ, Sala 9, São Paulo, SP, 05403-903, Brazil.
  • Klein I; Faculdade de Medicina da, Universidade de São Paulo, R. Dr. Ovídio Pires de Campos, 785-Cerqueira César, CEAPESQ, Sala 9, São Paulo, SP, 05403-903, Brazil.
  • Cavendish BA; Faculdade de Medicina da, Universidade de São Paulo, R. Dr. Ovídio Pires de Campos, 785-Cerqueira César, CEAPESQ, Sala 9, São Paulo, SP, 05403-903, Brazil.
  • Lee YH; Department of Psychiatry, Harvard Medical School and Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
  • Liu Z; Department of Psychiatry, Harvard Medical School and Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
  • Bauermeister J; Department of Psychiatry, University of Oxford, Oxford, UK.
  • Moreno ML; Faculdade de Medicina da, Universidade de São Paulo, R. Dr. Ovídio Pires de Campos, 785-Cerqueira César, CEAPESQ, Sala 9, São Paulo, SP, 05403-903, Brazil.
  • Viana MC; Centro de Pesquisa Clínica E Epidemiológica, Hospital Universitário, Universidade de São Paulo, São Paulo, Brazil.
  • Goulart AC; Department of Social Medicine, Postgraduate Program in Public Health, Center of Psychiatric Epidemiology (CEPEP), Federal University of Espírito Santo, Vitória, Brazil.
  • Santos IS; Centro de Pesquisa Clínica E Epidemiológica, Hospital Universitário, Universidade de São Paulo, São Paulo, Brazil.
  • Bauermeister S; Centro de Pesquisa Clínica E Epidemiológica, Hospital Universitário, Universidade de São Paulo, São Paulo, Brazil.
  • Smoller J; Departamento de Clínica Médica, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
  • Lotufo P; Department of Psychiatry, University of Oxford, Oxford, UK.
  • Benseñor IM; Department of Psychiatry, Harvard Medical School and Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
  • Brunoni AR; Faculdade de Medicina da, Universidade de São Paulo, R. Dr. Ovídio Pires de Campos, 785-Cerqueira César, CEAPESQ, Sala 9, São Paulo, SP, 05403-903, Brazil.
Soc Psychiatry Psychiatr Epidemiol ; 57(12): 2445-2455, 2022 Dec.
Article in English | MEDLINE | ID: covidwho-2035021
ABSTRACT

AIM:

Evidence indicates most people were resilient to the impact of the COVID-19 pandemic on mental health. However, evidence also suggests the pandemic effect on mental health may be heterogeneous. Therefore, we aimed to identify groups of trajectories of common mental disorders' (CMD) symptoms assessed before (2017-19) and during the COVID-19 pandemic (2020-2021), and to investigate predictors of trajectories.

METHODS:

We assessed 2,705 participants of the ELSA-Brasil COVID-19 Mental Health Cohort study who reported Clinical Interview Scheduled-Revised (CIS-R) data in 2017-19 and Depression Anxiety Stress Scale-21 (DASS-21) data in May-July 2020, July-September 2020, October-December 2020, and April-June 2021. We used an equi-percentile approach to link the CIS-R total score in 2017-19 with the DASS-21 total score. Group-based trajectory modeling was used to identify CMD trajectories and adjusted multinomial logistic regression was used to investigate predictors of trajectories.

RESULTS:

Six groups of CMD symptoms trajectories were identified low symptoms (17.6%), low-decreasing symptoms (13.7%), low-increasing symptoms (23.9%), moderate-decreasing symptoms (16.8%), low-increasing symptoms (23.3%), severe-decreasing symptoms (4.7%). The severe-decreasing trajectory was characterized by age < 60 years, female sex, low family income, sedentary behavior, previous mental disorders, and the experience of adverse events in life.

LIMITATIONS:

Pre-pandemic characteristics were associated with lack of response to assessments. Our occupational cohort sample is not representative.

CONCLUSION:

More than half of the sample presented low levels of CMD symptoms. Predictors of trajectories could be used to detect individuals at-risk for presenting CMD symptoms in the context of global adverse events.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Mental Disorders Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study / Qualitative research / Randomized controlled trials Limits: Female / Humans / Middle aged Country/Region as subject: South America / Brazil Language: English Journal: Soc Psychiatry Psychiatr Epidemiol Journal subject: Social Sciences / Epidemiology / Psychiatry Year: 2022 Document Type: Article Affiliation country: S00127-022-02365-0

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Mental Disorders Type of study: Cohort study / Diagnostic study / Experimental Studies / Observational study / Prognostic study / Qualitative research / Randomized controlled trials Limits: Female / Humans / Middle aged Country/Region as subject: South America / Brazil Language: English Journal: Soc Psychiatry Psychiatr Epidemiol Journal subject: Social Sciences / Epidemiology / Psychiatry Year: 2022 Document Type: Article Affiliation country: S00127-022-02365-0