Neutralizing antibody responses to SARS-CoV-2: A population based seroepidemiological analysis.
Indian J Med Microbiol
; 40(4): 585-587, 2022.
Article
in English
| MEDLINE | ID: covidwho-2036080
ABSTRACT
This study (August-September 2021) estimated the seroprevalence of SARS-CoV-2 neutralizing antibodies in the general population of Delhi and correlated it with their anti-SARS-CoV-2 IgG levels. Samples were selected by simple random sampling method. The neutralizing capacity was estimated by performing a surrogate virus neutralization test (sVNT) (GenScript), Piscataway, NJ, USA. A total of 2233 (87.1%, 95% C.I. 85.7, 88.3) of the 2564 SARS-CoV-2 IgG seropositive samples had detectable SARS-CoV-2 neutralizing antibodies. In samples with S/CO â≥ â4.00, the neutralizing antibodies ranged from 94.5% to 100%. The SARS-CoV-2 neutralizing antibody seroprevalence strongly correlated with the S/CO range of IgG SARS-CoV-2 (r â= â0.62, p â= â0.002).
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
SARS-CoV-2
/
COVID-19
Type of study:
Observational study
/
Randomized controlled trials
Topics:
Variants
Limits:
Humans
Language:
English
Journal:
Indian J Med Microbiol
Journal subject:
Microbiology
Year:
2022
Document Type:
Article
Affiliation country:
J.ijmmb.2022.07.009
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