Reaching a Tipping Point for Neurorehabilitation Research: Obstacles and Opportunities in Trial Design, Description, and Pooled Analysis.
Neurorehabil Neural Repair
; 36(10-11): 659-665, 2022 11.
Article
in English
| MEDLINE | ID: covidwho-2038589
ABSTRACT
The record-breaking pace of COVID-19 vaccine development and implementation depended heavily on collaboration among academic, government, and commercial stakeholders, especially through data-sharing and robust multicenter trials. Collaborative efforts have not been as fruitful in fields such as neurorehabilitation, where non-pharmacological interventions play a much larger role. Barriers to translating scientific advancements into clinical practice in neurorehabilitation include pervasively small study sizes, exacerbated by limited funding for non-pharmacological multicenter clinical trials; difficulty standardizing-and adequately describing-non-pharmacological interventions; and a lack of incentives for individual patient-level data-sharing. These barriers prevent reliable meta-analysis of non-pharmacological clinical studies in neurorehabilitation. This point-of-view will highlight these challenges as well as suggest practical steps that may be taken to improve the neurorehabilitation pipeline between evidence and implementation.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Neurological Rehabilitation
/
COVID-19
Type of study:
Prognostic study
/
Randomized controlled trials
/
Reviews
Topics:
Vaccines
Limits:
Humans
Language:
English
Journal:
Neurorehabil Neural Repair
Journal subject:
Neurology
/
Rehabilitation
Year:
2022
Document Type:
Article
Affiliation country:
15459683221124112
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