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TIMES TO ACT. Italian-Spanish-Polish-Uzbek Expert Forum Position Paper 2022. Dyslipidemia and arterial hypertension: The two most important and modifiable risk factors in clinical practice.
Filipiak, Krzysztof J; Babkowski, Miguel Camafort; Cameli, Matteo; Carugo, Stefano; Ferri, Claudio; Irisov, Djamshid B; Narkiewicz, Krzysztof; Nizamov, Ulugbek; Pérez de Isla, Leopoldo; Tomaszuk-Kazberuk, Anna; Ungar, Andrea; Gasecka, Aleksandra.
  • Filipiak KJ; Institute of Clinical Sciences, Maria Sklodowska-Curie Medical Academy, Warsaw, Poland.
  • Babkowski MC; Hypertension Unit, Hospital Clínic, University of Barcelona, Barcelona, Spain.
  • Cameli M; Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
  • Carugo S; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy; Cardiology Unit, Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico of Milan, Milan, Italy.
  • Ferri C; University of L'Aquila, MeSVA Department and San Salvatore Hospital, UOC Internal Medicine & Neohrology, Hypertension and Cardiovascular Prevention Unit, L'Aquila, Italy.
  • Irisov DB; Cardiac Arrhythmias Department, Republican Specialised Center of Cardiology, Tashkent, Uzbekistan.
  • Narkiewicz K; Chair and Department of Hypertension and Diabetology, Medical University of Gdansk, Gdansk, Poland.
  • Nizamov U; Department of Ischemic Heart Disease and Atherosclerosis, Republican Specialised Center of Cardiology, Tashkent, Uzbekistan.
  • Pérez de Isla L; Department of Cardiology, Hospital Clínico San Carlos, Madrid, Spain.
  • Tomaszuk-Kazberuk A; Department of Cardiology, Medical University of Bialystok, Bialystok, Poland.
  • Ungar A; Geriatric and Intensive Care Medicine, Hypertension Centre, University of Florence and Careggi Hospital, Florence, Italy.
  • Gasecka A; 1st Chair and Department of Cardiology, Medical University of Warsaw, Poland. gaseckaa@gmail.com.
Cardiol J ; 29(5): 730-738, 2022.
Article in English | MEDLINE | ID: covidwho-2040289
ABSTRACT
Hypertension and lipid disorders are two of the main cardiovascular risk factors. Both risk factors - if detected early enough - can be controlled and treated with modern, effective drugs, devoid of significant side effects, available in four countries as different as Italy, Spain, Poland, and Uzbekistan. The aim herein, was to develop this TIMES TO ACT consensus to raise the awareness of the available options of the modern and intensified dyslipidemia and arterial hypertension treatments. The subsequent paragraphs involves consensus and discussion of the deleterious effects of COVID-19 in the cardiovascular field, the high prevalence of hypertension and lipid disorders in our countries and the most important reasons for poor control of these two factors. Subsequently proposed, are currently the most efficient and safe therapeutic options in treating dyslipidemia and arterial hypertension, focusing on the benefits of single-pill combination (SPCs) in both conditions. An accelerated algorithm is proposed to start the treatment with a PCSK9 inhibitor, if the target low-density-lipoprotein values have not been reached. As most patients with hypertension and lipid disorders present with multiple comorbidities, discussed are the possibilities of using new SPCs, combining modern drugs from different therapeutic groups, which mode of action does not confirm the "class effect". We believe our consensus strongly advocates the need to search for patients with cardiovascular risk factors and intensify their lipid-lowering and antihypertensive treatment based on SPCs will improve the control of these two basic cardiovascular risk factors in Italy, Spain, Poland and Uzbekistan.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / Dyslipidemias / COVID-19 / Hypertension Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Country/Region as subject: Europa Language: English Journal: Cardiol J Year: 2022 Document Type: Article Affiliation country: CJ.a2022.0087

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / Dyslipidemias / COVID-19 / Hypertension Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Country/Region as subject: Europa Language: English Journal: Cardiol J Year: 2022 Document Type: Article Affiliation country: CJ.a2022.0087