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A distinct symptom pattern emerges for COVID-19 long-haul: a nationwide study.
Pinto, Melissa D; Downs, Charles A; Huang, Yong; El-Azab, Sarah A; Ramrakhiani, Nathan S; Barisano, Anthony; Yu, Lu; Taylor, Kaitlyn; Esperanca, Alvaro; Abrahim, Heather L; Hughes, Thomas; Herrera, Maria Giraldo; Rahamani, Amir M; Dutt, Nikil; Chakraborty, Rana; Mendiola, Christian; Lambert, Natalie.
  • Pinto MD; Sue & Bill Gross School of Nursing, University of California Irvine, Irvine, CA, USA. mdpinto@uci.edu.
  • Downs CA; University of Miami, Coral Gables, FL, USA.
  • Huang Y; Department of Computer Science, Donald Bren School of Information and Computer Science, University of California Irvine, Irvine, CA, USA.
  • El-Azab SA; Department of Health Management and Policy, University of Michigan, Lansing, MI, USA.
  • Ramrakhiani NS; Brown University, Providence, RI, USA.
  • Barisano A; Brown University, Providence, RI, USA.
  • Yu L; School of Labor and Employment Relations, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
  • Taylor K; Lambert Health Lab, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Esperanca A; Electrical and Computer Engineering Department, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA.
  • Abrahim HL; Sue & Bill Gross School of Nursing, University of California Irvine, Irvine, CA, USA.
  • Hughes T; Sue & Bill Gross School of Nursing, University of California Irvine, Irvine, CA, USA.
  • Herrera MG; Sue & Bill Gross School of Nursing, University of California Irvine, Irvine, CA, USA.
  • Rahamani AM; Sue & Bill Gross School of Nursing, University of California Irvine, Irvine, CA, USA.
  • Dutt N; Department of Computer Science, Donald Bren School of Information and Computer Science, University of California Irvine, Irvine, CA, USA.
  • Chakraborty R; Department of Computer Science, Donald Bren School of Information and Computer Science, University of California Irvine, Irvine, CA, USA.
  • Mendiola C; Division of Infectious Disease, Department of Pediatrics and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
  • Lambert N; School of Engineering and Technology, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA.
Sci Rep ; 12(1): 15905, 2022 09 23.
Article in English | MEDLINE | ID: covidwho-2042342
ABSTRACT
Long-haul COVID-19, also called post-acute sequelae of SARS-CoV-2 (PASC), is a new illness caused by SARS-CoV-2 infection and characterized by the persistence of symptoms. The purpose of this cross-sectional study was to identify a distinct and significant temporal pattern of PASC symptoms (symptom type and onset) among a nationwide sample of PASC survivors (n = 5652). The sample was randomly sorted into two independent samples for exploratory (EFA) and confirmatory factor analyses (CFA). Five factors emerged from the EFA (1) cold and flu-like symptoms, (2) change in smell and/or taste, (3) dyspnea and chest pain, (4) cognitive and visual problems, and (5) cardiac symptoms. The CFA had excellent model fit (x2 = 513.721, df = 207, p < 0.01, TLI = 0.952, CFI = 0.964, RMSEA = 0.024). These findings demonstrate a novel symptom pattern for PASC. These findings can enable nurses in the identification of at-risk patients and facilitate early, systematic symptom management strategies for PASC.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials / Systematic review/Meta Analysis Topics: Long Covid Limits: Humans Language: English Journal: Sci Rep Year: 2022 Document Type: Article Affiliation country: S41598-022-20214-7

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials / Systematic review/Meta Analysis Topics: Long Covid Limits: Humans Language: English Journal: Sci Rep Year: 2022 Document Type: Article Affiliation country: S41598-022-20214-7