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Current thromboprophylaxis in urological cancer patients during COVID-19 pandemic.
Ostrowski, Adam; Skrudlik, Piotr; Kowalski, Filip; Lipowski, Pawel; Ostrowska, Magdalena; Adamczyk, Przemyslaw; Adamowicz, Jan; Drewa, Tomasz; Juszczak, Kajetan.
  • Ostrowski A; Department of Urology and Andrology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
  • Skrudlik P; Department of Urology, NEO Hospital, Cracow, Poland.
  • Kowalski F; Department of Urology and Andrology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
  • Lipowski P; Department of Urology and Andrology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
  • Ostrowska M; Department of Urology and Andrology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
  • Adamczyk P; Department of Urology, Department of General and Oncologic Urology, Nicolaus Copernicus Hospital, Torun, Poland.
  • Adamowicz J; Department of Urology and Andrology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
  • Drewa T; Department of Urology and Andrology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
  • Juszczak K; Department of Urology and Andrology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Cent European J Urol ; 75(2): 128-134, 2022.
Article in English | MEDLINE | ID: covidwho-2044124
ABSTRACT

Introduction:

Venous thrombosis is a well-known complication of cancer disease, especially in Urology. However, even though proper antithrombotic prophylaxis is crucial in most urological procedures, we have insufficient high-quality studies on this topic. The European Association of Urology (EAU) Guidelines are outdated and lack data on COVID-19 increased risk of thrombosis. This review aimed to summarize data on thromboprophylaxis after radical prostatectomy, cystectomy, and nephrectomy during COVID-19 pandemic. Material and

methods:

A thorough analysis of the EAU Guidelines of Thromboprophylaxis was performed and compared to PubMed search, considering updated literature on thromboprophylaxis of radical prostatectomy, cystectomy, nephrectomy, as well as COVID-19 influence on venous thrombosis and urological practice.

Results:

Each patient should be evaluated individually to balance bleeding and venous thromboembolism (VTE) risk. There is still much uncertainty in low and medium-risk patients and all endoscopic procedures, where thromboprophylaxis could be omitted. Patients with COVID infection bear a significantly higher risk of VTE. All patients should be tested for COVID infection prior to a planned surgery during bursts of infections, undependably of vaccination status. Efforts to maintain early cancer diagnosis and treatment during the pandemic should be maintained.

Conclusions:

The quality of evidence is inadequate, and when deciding on thromboprophylaxis, we need to base it on individual risk, cancer advancement, procedure type, and our own experience.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Reviews Topics: Vaccines Language: English Journal: Cent European J Urol Year: 2022 Document Type: Article Affiliation country: Ceju.2022.0047

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Reviews Topics: Vaccines Language: English Journal: Cent European J Urol Year: 2022 Document Type: Article Affiliation country: Ceju.2022.0047