The potential of coconut oil and its derivatives as effective and safe antiviral agents against the novel coronavirus (nCoV-2019)
Indian Coconut Journal
; 64(7):23-26, 2022.
Article
in English
| CAB Abstracts | ID: covidwho-2045305
ABSTRACT
Monolaurin and lauric acid (C12) have demonstrated considerable viral activity. Lauric acid is a medium-chain fatty acid that accounts for around 50% of coconut oil;monolaurin is a metabolite produced by the body's enzymes after ingestion of coconut oil and is available as a supplement. Sodium lauryl sulfate, a lauric acid-based surfactant, exhibits antiviral properties. Several antiviral products contain lauric acid, monolaurin, and sodium lauryl sulfate (also known as sodium dodecyl sulfate). This article summarizes the 3 mechanisms proposed to explain the antiviral activity of lauric acid and monolaurin first, they cause virus envelope disintegration;second, they can inhibit late maturation in the virus replication cycle;and third, they can prevent viral proteins from binding to the host cell membrane. This article also discusses several in vitro, animal, and human research that support the potential of coconut oil, lauric acid, and its derivatives.
Crop Produce [QQ050]; Pesticides and Drugs; Control [HH405]; Non-food/Non-feed Plant Products [SS200]; Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210]; coconut oil; dodecanoic acid; in vitro; seed oils; antiviral properties; ingestion; polyacrylamide; sodium; coronavirus disease 2019; viral diseases; Severe acute respiratory syndrome coronavirus 2; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; lauric acid; anti-viral properties; SARS-CoV-2; viral infections
Search on Google
Collection:
Databases of international organizations
Database:
CAB Abstracts
Type of study:
Experimental Studies
Language:
English
Journal:
Indian Coconut Journal
Year:
2022
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS