Effect of miR-221-3p targeting TIMP-2 on proliferation and apoptosis of vascular smooth muscle cells in abdominal aortic aneurysm
Journal of Tropical Medicine
; 21(9):1119-1124, 2021.
Article
in Chinese
| CAB Abstracts | ID: covidwho-2047145
ABSTRACT
Objective:
To investigate the effects of miR-221-3p on the proliferation and apoptosis of vascular smooth muscle cells (VSMC) in abdominal aortic aneurysm (AAA) by targeting tissue inhibitor of metalloproteinase- 2 (TIMP-2).
Animal and in vitro Models for Pharmaceuticals [VV450]; Non-communicable Human Diseases and Injuries [VV600]; Molecular Biology and Molecular Genetics [ZZ360]; abdomen; aneurysm; angiotensin; aortic rupture; apoptosis; B lymphocytes; B-cell chronic lymphocytic leukaemia; cardiovascular system; cell lines; cells; gene expression; genes; human diseases; in vitro; metalloproteinases; muscle tissue; muscles; smooth muscle; vascular diseases; vascular system; viability; man; Severe acute respiratory syndrome coronavirus 2; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; B cells; circulatory system; SARS-CoV-2; blood vessel disorders
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Collection:
Databases of international organizations
Database:
CAB Abstracts
Type of study:
Experimental Studies
Language:
Chinese
Journal:
Journal of Tropical Medicine
Year:
2021
Document Type:
Article
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