Nanotechnology based Pathogen identification through surface marker identification

ABSTRACT

The demonic progression of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus) worldwide points out the need to develop innovative, rapid, and sensitive detection of microbial pathogens. Conventional molecular diagnostic techniques often require sophisticated, expensive instrumentation in addition to the high cost and shorter shelf life of some reagents. In contrast, the use of fluorescent quantum dots, carbon nanotube, etc., for pathogen detection can be tailored by changing surface charge ratio and particle size, which may provide global accessibility. The operating principle behind pathogen identification is the surface marker recognition of bacterial or viral nucleic acid sequences. Therefore this chapter aims to focus on the comprehensive utilization of nanotechnology in pathogen identification. The emerging technology of nano-based point-of-care detection and its association with the neural network is believed to mark a blueprint for diagnosing infectious diseases and improving human existence. © 2022 Elsevier Inc. All rights reserved.