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Intervention strategies with 2D cellular automata for testing SARS-CoV-2 and reopening the economy.
Lugo, Igor; Alatriste-Contreras, Martha G.
  • Lugo I; Centro Regional de Investigaciones Multidisciplinarias (CRIM), National Autonomous University of Mexico, 62210, Cuernavaca, Mor., Mexico. igorlugo@crim.unam.mx.
  • Alatriste-Contreras MG; Centro de Ciencias de la Complejidad (C3), National Autonomous University of Mexico, 04510, Mexico City, Mexico. igorlugo@crim.unam.mx.
Sci Rep ; 12(1): 13481, 2022 08 05.
Article in English | MEDLINE | ID: covidwho-2050507
ABSTRACT
During the period of time between a new disease outbreaks and its vaccine is deployed, the health and the economic systems have to find a testing strategy for reopening activities. In particular, asymptomatic individuals, who transmit locally the COVID-19 indoors, have to be identified and isolated. We proposed a 2D cellular automaton based on the SI epidemic model for selecting the most desirable testing frequency and identifying the best fitting size of random trails on local urban environments to diagnose SARS-CoV-2 and isolate infected people. We used the complex systems approach to face the challenge of a large-scale test strategy based on urban interventions, starting with first responders and essential workers. We used the case of Mexico to exemplify a credible and intelligent intervention that reduces the virus transmission and detects economic and health costs. Findings suggest that controlling and stopping the virus transmission in a short period of time are possible if the frequency of testing is daily and the percentage of random samples to be tested is at least 90%. This combination of model parameters represents the least expensive intervention compared to others. Therefore, the key for a national testing-isolating strategy is local interventions.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Sci Rep Year: 2022 Document Type: Article Affiliation country: S41598-022-17665-3

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study / Experimental Studies / Observational study / Randomized controlled trials Topics: Vaccines Limits: Humans Language: English Journal: Sci Rep Year: 2022 Document Type: Article Affiliation country: S41598-022-17665-3