Seroprevalence of SARS-CoV-2 in Mexican Health Care Workers after Two Years of the Pandemic: The Picture of an Ophthalmic Medical Centre.
Ophthalmic Epidemiol
; : 1-7, 2022 Oct 02.
Article
in English
| MEDLINE | ID: covidwho-2050888
ABSTRACT
OBJECTIVE:
In this study, we investigated the impact of the SARS-CoV-2 vaccination on seroprevalence in a cohort of healthcare workers (HCW) at an ophthalmic medical center.METHODS:
IgG antibodies against the N, S1, and S2 antigens of SARS-CoV-2 as well as their serum neutralizing activity were determined.RESULTS:
In the present study, we observed that 98.4% of HCW were seropositive for S1/S2 proteins of SARS-CoV-2 due to the national vaccination program. Interestingly, 78.4% of the participants had anti-N protein antibodies, suggesting previous COVID-19 infection. We also evaluated the neutralizing antibodies and found that the mean value was high (90.7%).CONCLUSION:
These results indicate that our HCWs cohort presented a robust hybrid humoral response owing to the massive national vaccination program and natural infections.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Vaccines
Country/Region as subject:
Mexico
Language:
English
Journal:
Ophthalmic Epidemiol
Journal subject:
Epidemiology
/
Ophthalmology
Year:
2022
Document Type:
Article
Affiliation country:
09286586.2022.2127789
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