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COVID-19 Exposure Assessment Tool (CEAT): Exposure quantification based on ventilation, infection prevalence, group characteristics, and behavior.
Schimmoller, Brian J; Trovão, Nídia S; Isbell, Molly; Goel, Chirag; Heck, Benjamin F; Archer, Tenley C; Cardinal, Klint D; Naik, Neil B; Dutta, Som; Rohr Daniel, Ahleah; Beheshti, Afshin.
  • Schimmoller BJ; Signature Science LLC, Austin, TX 78759, USA.
  • Trovão NS; COVID-19 International Research Team, Medford, MA 02155, USA.
  • Isbell M; COVID-19 International Research Team, Medford, MA 02155, USA.
  • Goel C; Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Heck BF; Signature Science LLC, Austin, TX 78759, USA.
  • Archer TC; COVID-19 International Research Team, Medford, MA 02155, USA.
  • Cardinal KD; Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Naik NB; Bastion Technologies, NASA Ames Research Center, Moffett Field, CA 94035, USA.
  • Dutta S; COVID-19 International Research Team, Medford, MA 02155, USA.
  • Rohr Daniel A; Biomea Fusion Inc., Redwood City, CA 94063, USA.
  • Beheshti A; Leidos Inc., NASA Ames Research Center, Moffett Field, CA 94035, USA.
Sci Adv ; 8(39): eabq0593, 2022 Sep 30.
Article in English | MEDLINE | ID: covidwho-2053089
ABSTRACT
The coronavirus disease 2019 (COVID-19) Exposure Assessment Tool (CEAT) allows users to compare respiratory relative risk to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for various scenarios, providing understanding of how combinations of protective measures affect risk. CEAT incorporates mechanistic, stochastic, and epidemiological factors including the (i) emission rate of virus, (ii) viral aerosol degradation and removal, (iii) duration of activity/exposure, (iv) inhalation rates, (v) ventilation rates (indoors/outdoors), (vi) volume of indoor space, (vii) filtration, (viii) mask use and effectiveness, (ix) distance between people (taking into account both near-field and far-field effects of proximity), (x) group size, (xi) current infection rates by variant, (xii) prevalence of infection and immunity in the community, (xiii) vaccination rates, and (xiv) implementation of COVID-19 testing procedures. CEAT applied to published studies of COVID-19 transmission events demonstrates the model's accuracy. We also show how health and safety professionals at NASA Ames Research Center used CEAT to manage potential risks posed by SARS-CoV-2 exposures.

Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Topics: Vaccines / Variants Language: English Journal: Sci Adv Year: 2022 Document Type: Article Affiliation country: Sciadv.abq0593

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study Topics: Vaccines / Variants Language: English Journal: Sci Adv Year: 2022 Document Type: Article Affiliation country: Sciadv.abq0593