Targeted detection and molecular epidemiology of turkey coronavirus spike gene variants in turkeys and chickens.
J Vet Diagn Invest
; 34(6): 955-959, 2022 Nov.
Article
in English
| MEDLINE | ID: covidwho-2053669
ABSTRACT
Turkey coronavirus (TCoV) is a member of the Avian coronavirus species with infectious bronchitis virus (IBV), which is considered to be the source of TCoV. These 2 viruses are highly similar in all regions of their genomes, except for the spike gene, which is necessary for virus attachment. Although TCoV causes severe enteric disease in turkey poults, it does not cause clinical disease in chickens. However, considering that TCoV can infect chickens, it is important to distinguish TCoV from IBV in chickens. This is particularly true for chickens that are housed near turkeys and thus might be infected with TCoV and serve as a silent source of TCoV for turkeys. We developed and validated a real-time PCR assay to detect the spike gene of TCoV and sequenced a portion of this gene to evaluate the molecular epidemiology of TCoV infections associated with a commercial turkey premises in the United States in 2020-2021. We identified natural infections of TCoV in chickens, and based on the molecular epidemiology of the viruses detected, these chickens may have served as a source of infection for the commercial turkey premises located nearby.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Poultry Diseases
/
Infectious bronchitis virus
/
Coronavirus, Turkey
/
Enteritis, Transmissible, of Turkeys
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Variants
Limits:
Animals
Language:
English
Journal:
J Vet Diagn Invest
Journal subject:
Veterinary Medicine
Year:
2022
Document Type:
Article
Affiliation country:
10406387221128610
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