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Biomaterials for Tissue Engineering Applications and Current Updates in the Field: A Comprehensive Review.
Eldeeb, Alaa Emad; Salah, Salwa; Elkasabgy, Nermeen A.
  • Eldeeb AE; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo, 11562, Egypt. Alaa.ali@pharma.cu.edu.eg.
  • Salah S; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo, 11562, Egypt.
  • Elkasabgy NA; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo, 11562, Egypt.
AAPS PharmSciTech ; 23(7): 267, 2022 Sep 26.
Article in English | MEDLINE | ID: covidwho-2054055
ABSTRACT
Tissue engineering has emerged as an interesting field nowadays; it focuses on accelerating the auto-healing mechanism of tissues rather than organ transplantation. It involves implanting an In Vitro cultured initiative tissue or a scaffold loaded with tissue regenerating ingredients at the damaged area. Both techniques are based on the use of biodegradable, biocompatible polymers as scaffolding materials which are either derived from natural (e.g. alginates, celluloses, and zein) or synthetic sources (e.g. PLGA, PCL, and PLA). This review discusses in detail the recent applications of different biomaterials in tissue engineering highlighting the targeted tissues besides the in vitro and in vivo key findings. As well, smart biomaterials (e.g. chitosan) are fascinating candidates in the field as they are capable of elucidating a chemical or physical transformation as response to external stimuli (e.g. temperature, pH, magnetic or electric fields). Recent trends in tissue engineering are summarized in this review highlighting the use of stem cells, 3D printing techniques, and the most recent 4D printing approach which relies on the use of smart biomaterials to produce a dynamic scaffold resembling the natural tissue. Furthermore, the application of advanced tissue engineering techniques provides hope for the researchers to recognize COVID-19/host interaction, also, it presents a promising solution to rejuvenate the destroyed lung tissues.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Zein / Chitosan / COVID-19 Limits: Humans Language: English Journal: AAPS PharmSciTech Journal subject: Pharmacology Year: 2022 Document Type: Article Affiliation country: S12249-022-02419-1

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Zein / Chitosan / COVID-19 Limits: Humans Language: English Journal: AAPS PharmSciTech Journal subject: Pharmacology Year: 2022 Document Type: Article Affiliation country: S12249-022-02419-1