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A Comprehensive Investigation of the Current Subacute Sclerosing Panencephalitis (SSPE) Treatment Options to Improve Patient Quality of Life.
Pritha, Ariana; Medha, Tanisha N; Garg, Ravindra K.
  • Pritha A; Neurosciences, The University of New Mexico, Albuquerque, USA.
  • Medha TN; Medicine, University of New Mexico, Albuquerque, USA.
  • Garg RK; Neurology, King George's Medical University, Lucknow, IND.
Cureus ; 14(8): e28389, 2022 Aug.
Article in English | MEDLINE | ID: covidwho-2056317
ABSTRACT
Subacute sclerosing panencephalitis (SSPE) is a progressive, disabling, and deadly neurological disorder related to measles (rubeola) infection occurring primarily in children. The slow but persistent viral infection occurs in children or young adults and affects their central nervous system (CNS). There have been plenty of reports on SSPE throughout the world, but it is considered a rare disease in developed countries. This research focuses on comparing the current treatments available to prolong the life of patients for over three years after the onset of SSPE. The goal was to identify possible patterns or trends among the treatments in order to find the best possible method to lengthen a patient's life. The results indicated that interferon alpha, inosine pranobex, and ribavirin display the most effective treatment plan and indicate the most potential in discovering a more effective therapeutic for SSPE.
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Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: Cureus Year: 2022 Document Type: Article Affiliation country: Cureus.28389

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Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: Cureus Year: 2022 Document Type: Article Affiliation country: Cureus.28389