The Effects of SARS-CoV-2 Infection on Renal Function in Patients with Hemodialysis

ABSTRACT

Objective: This study aims to demonstrate the impact of "SARS-CoV-2" infection on renal function in patients who have undergone hemodialysis in the past. Methodology: Telomerase Reverse Polymerase Chain Reaction in Real Time (RT-Real time PCR) To verify "SARS CoV-2" infection, RT-PCR was used, moreover pre and post urea and creatinine tests were confirmed by COBAS INTEGRA 400 plus analyzer was automated qualitative assays rapidly detected Creatinine, urea, and diabetes Mellitus levels. Result(s) The mean of pre-creatinine levels was 7.3336. The post-creatinine levels (11.8276) significantly increased after "SARS-CoV-2" infection with a P-value of 0.001. The mean of pre-urea levels was 163.6724. The post-urea levels (213.706897) significantly increased after "SARS-CoV-2" infection with a P-value of 0.001. Conclusion(s) SARS-CoV-2 infection in patients with pre-existing hemodialysis leads to increasing kidney dysfunction with or without comorbidities (diabetes mellitus and hypertension). Moreover, the old patients with pre-existing hemodialysis are found to be at higher risk of renal dysfunction during "SARS-CoV-2" infection than the younger groups. Copyright © 2022, Bahrain Medical Bulletin. All rights reserved.