Allergy and COVID Vaccines
Journal of Comprehensive Pediatrics
; 13(Supplement 1):5, 2022.
Article
in English
| EMBASE | ID: covidwho-2057539
ABSTRACT
We have been experiencing more allergic reactions to vaccines during the recent pandemic. Severe allergic reactions to vaccines are rare and difficult to predict. It might be defined as an idiosyncratic reaction caused by an immunologic mechanism. Regarding the World Allergy Organization (WAO) recommendation, immunologic reactions to drugs are categorized based upon the timing of the appearance of symptoms. This system defines two general types of reactions immediate and delayed. Recently COVID vaccines are broadly applied worldwide. The CDC has provided the following differentiation (1) contraindication persons with a known (diagnosed) allergy to PEG, polysorbate, or another component of a COVID-19 vaccine or who have experienced a severe allergic reaction (e.g., anaphylaxis) after a previous COVID-19 vaccine dose have a contraindication to vaccination;(2) precaution persons with an immediate allergic reaction to other (non-COVID-19) vaccines or injectable therapies OR a non-severe immediate allergic reaction (onset < 4 hours) after a previous dose of COVID-19 vaccine fall into this category. May proceed with COVID-19 vaccine (1) persons with a history of food, pet, insect, venom, environmental, oral medication (including the oral equivalent of an injectable medication) or latex allergies;or (2) a family history of allergies. Other reactions like vaccineinduced immune thrombotic thrombocytopenia (VITT) or thrombosis-thrombocytopenia syndrome (TTS) have been reported with adenoviral vector covid-19 vaccines. Myocarditis/pericarditis and Guillain-Barre Syndrome are also reported with COVID vaccines. Results of safety monitoring from VAERS and V-safe after one month of vaccinations show that over 90% of reactions were nonserious. Anaphylaxis rates (4.5 per million doses) remain in the range of other vaccines. The female gender may be a risk factor for adverse reactions and anaphylaxis. To sum up, COVID vaccines are very safe, and severe allergic reactions are exceedingly rare.
Allergy; covid-19; Vaccine; adult; anaphylaxis; conference abstract; contraindication; controlled study; coronavirus disease 2019; drug therapy; family history; female; gender; Guillain Barre syndrome; human; latex allergy; male; myocarditis; oral drug administration; pericarditis; risk factor; side effect; thrombotic thrombocytopenic purpura; vaccination; adenovirus vector; insect venom; polysorbate; SARS-CoV-2 vaccine
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Collection:
Databases of international organizations
Database:
EMBASE
Topics:
Vaccines
Language:
English
Journal:
Journal of Comprehensive Pediatrics
Year:
2022
Document Type:
Article
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