The Pragmatic Role of COVID-19 on the Thrombus Grade of Patients with Contemporary ST-Segment-Elevation Myocardial Infarction
Journal of Tehran University Heart Center
; 17(3):103-111, 2022.
Article
in English
| EMBASE | ID: covidwho-2057796
ABSTRACT
Background:
Limited data exist on the clinical outcomes of patients with coronavirus disease 2019 (COVID-19) presenting with ST-segment-elevation myocardial infarction (STEMI). Method(s) This multicenter study, conducted in 6 centers in Iran, aimed to compare baseline clinical and procedural data between a case group, comprising STEMI patients with COVID-19, and a control group, comprising STEMI patients before the COVID-19 pandemic, and to determine in-hospital infarct-related artery thrombus grades and major adverse cardio-cerebrovascular events (MACCEs), defined as a composite of deaths from any cause (cardiovascular and noncardiovascular), nonfatal strokes, and stent thrombosis. Result(s) No significant differences were observed between the 2 groups regarding baseline characteristics. Primary percutaneous coronary intervention (PPCI) was performed in 72.9% of the cases and 98.5% of the controls (P=0.043), and primary coronary artery bypass grafting was performed in 6.2% of the cases and 1.4% of the controls (P=0.048). Successful PPCI procedures (final TIMI flow grade III) were significantly fewer in the case group (66.5% vs 93.5%;P=0.001). The baseline thrombus grade before wire crossing was not statistically significantly different between the 2 groups. The summation of thrombus grades IV and V was 75% in the case group and 82% in the control group (P=0.432). The rate of MACCEs was 14.5% and 2.1% in the case and control groups, respectively (P=0.002). Conclusion(s) In our study, the thrombus grade had no significant differences between the case and control groups;however, the in-hospital rates of the no-reflow phenomenon, periprocedural MI, mechanical complications, and MACCEs were statistically significantly higher in the case group. Copyright © 2022 Tehran University of Medical Sciences.
covid-19; Primary PCI; stemi; Thrombus burden; adult; adverse device effect; all cause mortality; artery thrombosis; article; case report; cerebrovascular accident; cerebrovascular disease; clinical article; complication; coronary artery bypass graft; coronavirus disease 2019; female; hospital charge; human; Iran; male; multicenter study; no reflow phenomenon; pandemic; percutaneous coronary intervention; ST segment elevation myocardial infarction; stent thrombosis; surgery; thrombus
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Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Journal of Tehran University Heart Center
Year:
2022
Document Type:
Article
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