Lab Parameter among Corona Patients
European Journal of Molecular and Clinical Medicine
; 9(6):1075-1083, 2022.
Article
in English
| EMBASE | ID: covidwho-2058068
ABSTRACT
Introduction:
The COVID-19 pandemic has been raging across the globe since early January 2020. Various geographical regions have been passing multiple swells of upsurge of cases which aren't matched temporally as well as in severity. The diapason of the complaint ranges from asymptomatic to severe life-hanging complaint. Advanced age and the presence of comorbidities similar as cardiovascular complaint, diabetes mellitus, hypertension, chronic lung complaint, chronic kidney complaint, cancer, and obesity are among the major threat factors for severe disease. Aims andobjectives:
Significance of lab parameter among Corona Patients. Materials andmethods:
The covid- 19 opinion was verified by reverse transcription- polymerase chain reaction (RT- PCR) assay of nasopharyngeal swab sample. Hematology blood samples were used to analyze by flow cytometry. Biochemical samples were used to analyze by completely auto analyzer diagnostic outfit. Serology tests were carried out the styles based on indirect ELISA technique, immune plates are coated with a admixture of purified viral antigen and probe using the patient serum.Results:
It is found that there is statistically significant (p-value<0.05) mean difference within the lab parameters (IL-6, LDH and Ferritin) in Covid patients using the Post Hoc Analysis. It is also found that there statistically significant (p-value<0.05) mean difference between RBC, Hb level, Hematocrit, MCV, MCH, MCHC, Platelet, RDW, PCT and NL ratio while Age, WBC, MPV, M(Monocyte), E(Eosinophil), B(Basophil), D-dimer and PDW were found to be statistically insignificant (p-value>0.05) with respect to gender.Discussion:
CBC, D- dimer, IL-6, LDH and Ferritin were analysed and found associated with adverse outcomes. There is significant association of age, gender, comorbidity.Conclusion:
High NLR at admission associated with a higher mortality. Laboratory features (e.g., IL-6, LDH, Ferritin D-dimer etc.) were associated with poor outcomes.
adult; advanced cancer; adverse outcome; age; article; autoanalyzer; basophil; blood sampling; cancer patient; case report; clinical article; comorbidity; coronavirus disease 2019; diabetes mellitus; eosinophil; female; flow cytometry; gender; hematocrit; hematology; human; human cell; human tissue; hypertension; indirect ELISA; kidney; lung; male; malignant neoplasm; mean corpuscular hemoglobin; mean corpuscular hemoglobin concentration; monocyte; mortality; nasopharyngeal swab; obesity; outcome assessment; platelet distribution width; post hoc analysis; reverse transcription polymerase chain reaction; serology; D dimer; endogenous compound; ferritin; interleukin 6; virus antigen
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Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
European Journal of Molecular and Clinical Medicine
Year:
2022
Document Type:
Article
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