Side Effects and Contraindications of COVID-19 Vaccines

ABSTRACT

The side effects of COVID-19 vaccines can be divided into three categories (1) common but non-significant complications;(2) uncommon but significant complications;(3) complications that currently have no causal relationship with the COVID-19 vaccine and are more commonly referred to as associations. Non-significant complications can be local or systemic, such as pain at the injection site, swelling, redness, axillary lymphadenopathy on the injection site, fever, chills, headache, nausea, tiredness, joints pain, nausea and vomiting. Significant side effects include the following four (1) anaphylaxis;(2) myocarditis/ pericarditis;(3) thrombosis with thrombocytopenia syndrome (TTS);(4) Guillain-Barre syndrome. Cases such as tinnitus, Bell's palsy, pulmonary embolism, and deep vein thrombosis (DVT) without further thrombocytope18 nia are now referred to as associations. Thrombosis with Thrombocytopenia Syndrome Currently, adenovirus vector vaccines such as AstraZeneca and Johnson & Johnson vaccines are accused of causing these two complications, and mRNA vaccines have not been shown to produce such a complication. Myocarditis/Pericarditis mRNA vaccines such as Pfizer and Moderna have been implicated in causing this complication, and no adenovirus vector vaccines such as Johnson & Johnson have been reported. Contraindications to the Injection of COVID-19 Vaccines Any immediate allergic reaction to the vaccine or its associated ingredients with any severity such as anaphylaxis and urticaria that occurs within 4 hours of injection. Precautions for COVID-19 Vaccines History of any Immediate Allergies to Other Vaccines and Injectable Drugs A history of anaphylaxis to mRNA vaccines for Johnson & Johnson vaccine and a history of anaphylaxis to Johnson & Johnson vaccine for mRNA vaccines is considered a precaution. If you have a history of heparin-induced thrombocytopenia within the last 90 days, the CDC recommends that you do not get AstraZeneca, and Johnson & Johnson vaccine. However, a history of any thrombotic events without thrombocytopenia is not prohibited for any type of corona vaccine. Items that are Neither Contraindications nor Precautions Presence of erythematous skin lesions with a sharp border at the injection site, usually one week after receiving the mRNA vaccine Consumption of Anticoagulants Swelling of the face at the site of application of cosmetic skin fillers following the use of mRNA vaccine.