COVID-19 Disease in Kidney Transplant Recipients
Revista de Nefrologia, Dialisis y Trasplante
; 42(3):181-188, 2022.
Article
in English
| EMBASE | ID: covidwho-2058474
ABSTRACT
Aim:
Coronavirus infection can lead to severe acute respiratory distress syndrome. Information on COVÍD-19 infection in patients with kidney transplants (KT) is lacking yet. In our study, clinical, radiological, laboratory features and clinical course of COVÍD-19 infection in these patients were investigated.Methods:
We retrospectively investigated KT recipient patients with COVID-19 diagnosed between March 15, 2020, and December 15, 2020. Clinical, radiological, laboratory features and clinical course of COVID-19 infection in these patients were recorded.Results:
We identified 23 KT recipient patients with COVID-19 infection. Eighteen KT patients (78.3%) had positive reverse transcription polymerase chain reaction (RT-PCR) results for COVID-19, 5 patients (21.7%) were negative. Twelve KT patients (52.2%) were male and 11 (47.8%) were female. Fifteen of the KT patients (65.2%) had comorbidity. Thorax computed tomography showed infiltrations in 21 KT patients (91.3%). There were 14 patients (60.8%) with glomerular filtration rate (GFR) below 60 ml/ min, who were considered acute renal failure. One patient needed plasma treatment, 2 needed hemodialysis. Mortality rate was 26%.Conclusion:
COVÍD-19 infection causes kidney failure in patients with kidney transplant. Mortality is high in kidney transplant patients with COVÍD-19 infection. Suggested poor prognostic factors increasing death risk are being 60 years or older, recent transplantation, low oxygen saturation level, high WBC count, high CRP level, high troponin level, high D-dimer level, high creatinine level, low GFR value, low sodium level.
acute kidney failure; adult; adult respiratory distress syndrome; article; clinical article; comorbidity; computer assisted tomography; controlled study; coronavirus disease 2019; female; gene expression; glomerulus filtration rate; hemodialysis; human; human tissue; kidney disease; kidney failure; kidney graft; kidney transplantation; leukocyte count; male; mortality; mortality rate; oxygen saturation; retrospective study; reverse transcription polymerase chain reaction; surgery; thorax; creatinine; D dimer; endogenous compound; sodium; troponin
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Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Revista de Nefrologia, Dialisis y Trasplante
Year:
2022
Document Type:
Article
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