Revisiting scrub typhus: A neglected tropical disease.
Comp Immunol Microbiol Infect Dis
; 90-91: 101888, 2022.
Article
in English
| MEDLINE | ID: covidwho-2252073
ABSTRACT
Scrub typhus is an under diagnosed re-emerging vector borne disease caused by an intracellular gram negative bacteria, Orientia. The disease is commonly prevalent in rural and hilly areas of Tsutsugumashi triangle. The diagnosis of the disease is very challenging due to similarity of its early symptoms with other febrile illnesses, like dengue and COVID 19, as well as non-availability of rapid, reliable and cost-effective methods. Moreover, the diverse clinical presentation in severe cases make it significant health problem. The occupational and behavioral risks responsible for the transmission lead to urgent need of vaccine development against the disease. The complete knowledge about its pathogenesis and the interaction with host's immune cells may help the scientists in developing the appropriate diagnostic methods as well as the vaccines.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Orientia tsutsugamushi
/
Scrub Typhus
/
Vaccines
/
Neglected Diseases
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Topics:
Vaccines
Limits:
Animals
Language:
English
Journal:
Comp Immunol Microbiol Infect Dis
Year:
2022
Document Type:
Article
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