Treatment of Orbital Desmoid-type Fibromatosis With Sorafenib.
Ophthalmic Plast Reconstr Surg
; 38(5): e144-e147, 2022.
Article
in English
| MEDLINE | ID: covidwho-2063057
ABSTRACT
Desmoid-type fibromatosis is a rare tumor, particularly in the orbit, with fewer than 10 cases of primary orbital desmoid-type fibromatosis reported in the literature. The authors present a case of an infant who presented with rapid onset of OD proptosis, disc edema, and hyperopic shift who was found to have a retrobulbar desmoid-type fibromatosis. After initial biopsy, due to risk of vision loss with complete excision, the tumor was treated with sorafenib, a tyrosine kinase inhibitor. During the course of treatment with sorafenib, the tumor stabilized and then regressed in size. To the authors' knowledge, this is the first reported case of orbital desmoid-type fibromatosis to be treated with sorafenib.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Fibromatosis, Aggressive
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
Limits:
Humans
/
Infant
Language:
English
Journal:
Ophthalmic Plast Reconstr Surg
Journal subject:
Ophthalmology
Year:
2022
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS