Surgical Management of Rhino-Orbito-Cerebral Mucormycosis Post-COVID-19 Infection
Otolaryngology - Head and Neck Surgery
; 167(1 Supplement):P150, 2022.
Article
in English
| EMBASE | ID: covidwho-2064481
ABSTRACT
Introduction:
The pandemic of COVID-19 in association with mucormycosis would be a deadly fungal infection with high level of mortality and morbidity. Our aim is to evaluate the surgical outcome of patients with rhino-orbito-cerebral mucormycosis to suggest better management strategies. Method(s) A total of 62 cases of COVID-19-associated rhino-orbito-cerebral mucormycosis were admitted to the ear, nose, throat department in Mashhad, Iran, from August 1 to October 15, 2021. All data were analyzed using SPSS version 27.0. Descriptive analysis was used for demographic and clinical characteristics. Result(s) Main predisposing conditions were diabetes mellitus (90%) followed by hypertension (41%). Main symptoms were headache (75%), periorbital or retro-orbital pain (61%), visual loss (45%), and facial numbness (41%). Mucosal and ocular findings showed necrosis (67%), blindness (n=35), ptosis (n=31), proptosis (n=27), ophthalmoplegia (n=25), and chemosis (n=20). Neurologic loss of consciousness (19%) and palsies of cranial nerves (53%) were observed. Endoscopy findings showed necrosis (70%), discharge (61%), and crusting (54%). Imaging enhancement revealed mucosal thickening (69%), opacification of sinus (69%), bony destruction of sinus (35%), and orbital involvement (25%). Debridement surgery was necessary in nearly all patients (96%), dominated by ethmoid sinus (90%), maxillary sinus (87%), middle turbinate (80%), and sphenoid sinus (79%). Based on our follow-up, 25 patients died (42%). Those who survived will suffer from no light perception (35%), cranial nerve palsy (12%), and cerebral vascular accident (1.6%). Conclusion(s) Mucormycosis is an aggressive fungal infection. Diabetes mellitus, COVID-19 complication, inappropriate use of corticosteroids, and delayed vaccination had significantly increased its incidence. As there is an urgent need to address this public health concern, we present our data set from Iran.
adult; blindness; cerebrovascular accident; chemosis; clinical feature; complication; conference abstract; coronavirus disease 2019; cranial nerve paralysis; data analysis software; debridement; demography; destruction; diabetes mellitus; ear; endoscopy; ethmoid sinus; exophthalmos; eye pain; face; female; follow up; headache; human; hypertension; hypesthesia; incidence; Iran; major clinical study; male; maxillary sinus; mucormycosis; mycosis; necrosis; ophthalmoplegia; outcome assessment; photoreactivity; public health; sphenoid sinus; surgery; throat; turbinate; unconsciousness; vaccination; corticosteroid
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Topics:
Long Covid
Language:
English
Journal:
Otolaryngology - Head and Neck Surgery
Year:
2022
Document Type:
Article
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