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Associations of COVID-19 Outcomes with Dialysis Modalities and Settings.
Weinhandl, Eric D; Liu, Jiannong; Gilbertson, David T; Wetmore, James B; Johansen, Kirsten L.
  • Weinhandl ED; Chronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota.
  • Liu J; Department of Pharmaceutical Care and Health Systems, University of Minnesota, Minneapolis, Minnesota.
  • Gilbertson DT; Chronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota.
  • Wetmore JB; Chronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota.
  • Johansen KL; Chronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota.
Clin J Am Soc Nephrol ; 17(10): 1526-1534, 2022 Oct.
Article in English | MEDLINE | ID: covidwho-2065333
ABSTRACT
How maintenance dialysis modality, dialysis setting, and residence in a nursing facility have jointly associated with coronavirus disease 2019 (COVID-19)-related outcomes in the United States is relevant to future viral outbreaks. Using Medicare claims, we determined the incidence of COVID-19-related infection, hospitalization, and death between March 15, 2020 and June 5, 2021. The exposure was one of five combinations of dialysis modality and care

setting:

in-facility hemodialysis without a recent history of skilled nursing facility care, in-facility hemodialysis with a recent history of skilled nursing facility care, hemodialysis in a skilled nursing facility, home hemodialysis, and (home) peritoneal dialysis. Patient-weeks were pooled to estimate the adjusted associations of event incidence with each dialysis modality/setting during four intervals in 2020-2021. Relative to in-facility hemodialysis without a recent history of skilled nursing facility care, home dialysis was associated with 36%-60% lower odds of all events during weeks 12-23 of 2020; 24%-37% lower odds of all events during weeks 24-37 of 2020; 20%-33% lower odds of infection and hospitalization during the winter of 2020-2021; and similar odds of all events thereafter. In contrast, exposure to skilled nursing facilities was associated with 570%-1140% higher odds of all events during spring of 2020, although excess risk attenuated as the pandemic transpired, especially among patients who received hemodialysis in skilled nursing facilities. In conclusion, home dialysis was associated with lower risks of COVID-19 diagnosis, hospitalization, and death until vaccines were available, whereas care in skilled nursing facilities was associated with higher risks.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Renal Dialysis / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Topics: Vaccines / Variants Limits: Aged / Humans Country/Region as subject: North America Language: English Journal: Clin J Am Soc Nephrol Journal subject: Nephrology Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Renal Dialysis / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study Topics: Vaccines / Variants Limits: Aged / Humans Country/Region as subject: North America Language: English Journal: Clin J Am Soc Nephrol Journal subject: Nephrology Year: 2022 Document Type: Article