Inspiration to mRNA-based COVID-19 vaccination: Serious adverse case reports with hepatitis B vaccine in real-world.
Front Pediatr
; 10: 888686, 2022.
Article
in English
| MEDLINE | ID: covidwho-2065607
ABSTRACT
Objectives:
The hepatitis B vaccine comprises hepatitis B surface antigen (HBsAg) produced by transgenic yeast cells. There are few serious adverse events (SAE) reports after Hepatitis B vaccination.Methods:
The authors searched the Chinese legal documents database for all SAE with Hepatitis B vaccination from January 2010 to January 2022.Results:
All seven patients received yeast-derived recombinant hepatitis B vaccine. Three cases of myocarditis (death), 2 cases of interstitial pneumonia (death), and 2 cases of encephalitis. The mean time of onset of SAE was 8.3 ± 4.3 h after vaccination.Conclusion:
The mechanism of vaccine-induced myocarditis may come from immune protein reactions. Based on the experience of Hepatitis B vaccine adverse events, we present new insights into the mechanism of myocarditis caused by the COVID-19 vaccine.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Case report
Topics:
Vaccines
Language:
English
Journal:
Front Pediatr
Year:
2022
Document Type:
Article
Affiliation country:
Fped.2022.888686
Similar
MEDLINE
...
LILACS
LIS