Marine Natural Products in Clinical Use.
Mar Drugs
; 20(8)2022 Aug 18.
Article
in English
| MEDLINE | ID: covidwho-2066237
ABSTRACT
Marine natural products are potent and promising sources of drugs among other natural products of plant, animal, and microbial origin. To date, 20 drugs from marine sources are in clinical use. Most approved marine compounds are antineoplastic, but some are also used for chronic neuropathic pain, for heparin overdosage, as haptens and vaccine carriers, and for omega-3 fatty-acid supplementation in the diet. Marine drugs have diverse structural characteristics and mechanisms of action. A considerable increase in the number of marine drugs approved for clinical use has occurred in the past few decades, which may be attributed to increasing research on marine compounds in laboratories across the world. In the present manuscript, we comprehensively studied all marine drugs that have been successfully used in the clinic. Researchers and clinicians are hopeful to discover many more drugs, as a large number of marine natural compounds are being investigated in preclinical and clinical studies.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Biological Products
/
Antineoplastic Agents
Type of study:
Prognostic study
Topics:
Vaccines
Limits:
Animals
Language:
English
Journal subject:
Biology
/
Pharmacology
Year:
2022
Document Type:
Article
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