Different routine laboratory tests in assessment of COVID-19: A case-control study
Journal of Acute Disease
; 11(4):140-149, 2022.
Article
in English
| EMBASE | ID: covidwho-2066825
ABSTRACT
Objective:
To identify helpful laboratory paprameters for the diagnosis and prognosis of COVID-19.Methods:
An observational retrospective study was conducted to analyze the biological profile of COVID-19 patients hospitalized in the Unit of Pulmonology at Setif hospital between January and December 2021. Patients were divided into two groups the infection group and the control group with patients admitted for other pathologies. The infected group was further divided according to the course of the disease into non-severe and severe subgroups. Clinical and laboratory parameters and outcomes of admitted patients were collected.Results:
The infection group included 293 patients, of whom 237 were in the non-severe subgroup and 56 in the severe subgroup. The control group included 88 patients. The results showed higher white blood cells, neutrophils, blood glucose, urea, creatinine, transaminases, triglycerides, C-reactive protein, lactate dehydrogenase, and lower levels of lymphocyte, monocyte and platelet counts, serum sodium concentration, and albumin. According to ROC curves, urea, alanine aminotransferase, C-reactive protein, and albumin were effective diagnosis indices on admission while neutrophil, lymphocyte, monocyte, glycemia, aspartate aminotransferase, and lactate dehydrogenase were effective during follow-up.Conclusions:
Some biological parameters such as neutrophil, lymphocyte, monocyte, glycemia, aspartate aminotransferase, and lactate dehydrogenase are useful for the diagnosis of COVID-19.
alanine aminotransferase; albumin; aminotransferase; antidiabetic agent; antihypertensive agent; aspartate aminotransferase; C reactive protein; creatinine; D dimer; fibrinogen; hemoglobin; lactate dehydrogenase; procalcitonin; prothrombin; sodium; triacylglycerol; urea; adolescent; adult; aged; Algeria; article; case control study; clinical assessment; clinical laboratory; comorbidity; controlled study; coronavirus disease 2019; diabetes mellitus; disease course; female; follow up; glucose blood level; heart disease; hospital admission; hospitalization; human; human tissue; hypertension; laboratory test; leukocyte count; lymphocyte count; major clinical study; male; monocyte count; neutrophil count; outcome assessment; platelet count; prostate hypertrophy; pulmonology; receiver operating characteristic; respiratory tract disease; retrospective study; social status; sodium blood level; symptom; very elderly
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Observational study
Language:
English
Journal:
Journal of Acute Disease
Year:
2022
Document Type:
Article
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