A review: The phytochemistry, pharmacology, and pharmacokinetics of Curcumae Longae Rhizoma (Turmeric)
World Journal of Traditional Chinese Medicine
; 8(4):463-490, 2022.
Article
in English
| EMBASE | ID: covidwho-2066828
ABSTRACT
Curcumae Longae Rhizoma (CLR) is the rhizome of Curcuma longa L. Pharmacological studies show that CLR can be used to treat cervical cancer, lung cancer, lupus nephritis, and other conditions. In this paper, we review botany, traditional application, phytochemistry, pharmacological activity, and pharmacokinetics of CLR. The literature from 1981 to date was entirely collected from online databases, such as Web of Science, Google Scholar, China Academic Journals full-text database (CNKI), Wiley, Springer, PubMed, and ScienceDirect. The data were also obtained from ancient books, theses and dissertations, and Flora Reipublicae Popularis Sinicae. There are a total of 275 compounds that have been isolated from CLR, including phenolic compounds, volatile oils, and others. The therapeutic effect of turmeric has been expanded from breaking blood and activating qi in the traditional sense to antitumor, anti-inflammatory, antioxidation, neuroprotection, antibacterial, hypolipidemic effects, and other benefits. However, the active ingredients and mechanisms of action related to relieving disease remain ill defined, which requires more in-depth research and verification at a clinical level.
liquid chromatograph; mass spectrometer; ampicillin; antiinfective agent; antioxidant; bleomycin; Curcuma longa extract; curcumin; dexamethasone; diclofenac; essential oil; herbicide; paraquat; phenol derivative; prednisone acetate; propolis; turmeric; vincristine; angiogenesis; antibacterial activity; antineoplastic activity; antioxidant activity; arthralgia; asthma; bleomycin-induced pulmonary fibrosis; botany; cerebrovascular disease; chemical structure; China; Chinese medicine; colorectal cancer; coronavirus disease 2019; Curcuma longa; depression; drug activity; drug capsule; drug granule; ear edema; esophagus cancer; ethnopharmacology; experimental autoimmune neuritis; flora; Gram negative bacterium; Gram positive bacterium; human; hyperlipidemia; hypolipidemic activity; inductively coupled plasma atomic emission spectrometry; inflammation; insulin resistance; JAK-STAT signaling; liniment; lipid peroxidation; malignant neoplasm; MAPK signaling; melanoma; minimum inhibitory concentration; multidrug resistance; nanotechnology; neoplasm; neuroprotection; nonhuman; oxidative stress; paste; phytochemistry; pill; powder; prescription; review; rheumatic disease; rhizome; scientific literature; synergistic effect; tablet; therapy effect; traditional medicine; traumatic brain injury; uterine cervix cancer
Full text:
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Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
World Journal of Traditional Chinese Medicine
Year:
2022
Document Type:
Article
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