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Clinical-epidemiologic variation in patients treated in the first and second wave of COVID-19 in Lambayeque, Peru: A cluster analysis.
Valladares-Garrido, Mario J; Failoc-Rojas, Virgilio E; Soto-Becerra, Percy; Zeña-Ñañez, Sandra; Torres-Roman, J Smith; Fernández-Mogollón, Jorge L; Colchado-Palacios, Irina G; Apolaya-Segura, Carlos E; Dávila-Gonzales, Jhoni A; Arce-Villalobos, Laura R; Neciosup-Puican, Roxana Del Pilar; Calvay-Requejo, Alexander G; Maguiña, Jorge L; Apolaya-Segura, Moisés; Díaz-Vélez, Cristian.
  • Valladares-Garrido MJ; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; South American Center for Education and Research in Public Health, Universidad Norbert Wiener, Lima, Peru.
  • Failoc-Rojas VE; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Universidad San Ignacio de Loyola, Lima, Peru. Electronic address: virgiliofr@gmail.com.
  • Soto-Becerra P; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Universidad Continental, Huancayo, Peru.
  • Zeña-Ñañez S; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Universidad Continental, Huancayo, Peru.
  • Torres-Roman JS; Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, Peru.
  • Fernández-Mogollón JL; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru.
  • Colchado-Palacios IG; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru.
  • Apolaya-Segura CE; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru.
  • Dávila-Gonzales JA; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru.
  • Arce-Villalobos LR; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru.
  • Neciosup-Puican RDP; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru.
  • Calvay-Requejo AG; Hospital Nacional Almanzor Aguinaga Asenjo, EsSalud, Chiclayo, Peru.
  • Maguiña JL; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, Peru.
  • Apolaya-Segura M; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Facultad de Medicina, Universidad Cesar Vallejo, Chiclayo, Peru.
  • Díaz-Vélez C; Instituto de Evaluación de Tecnologías en Salud e Investigación - IETSI, EsSalud, Lima, Peru; Facultad de Medicina, Universidad Privada Antenor Orrego, Trujillo, Peru.
Int J Infect Dis ; 123: 212-220, 2022 Oct.
Article in English | MEDLINE | ID: covidwho-2069127
ABSTRACT

OBJECTIVES:

To identify differences in the clinical and epidemiologic characteristics of patients during the first and second waves of the COVID-19 pandemic at the EsSalud Lambayeque health care network, Peru.

METHODS:

An analytical cross-sectional study of 53,912 patients enrolled during the first and second waves of COVID-19 was conducted. Cluster analysis based on clustering large applications (CLARA) was applied to clinical-epidemiologic data presented at the time of care. The two pandemic waves were compared using clinical-epidemiologic data from epidemiologic surveillance.

RESULTS:

Cluster analysis identified four COVID-19 groups with a characteristic pattern. Cluster 1 included the largest number of participants in both waves, and the participants were predominantly female. Cluster 2 included patients with gastrointestinal, respiratory, and systemic symptoms. Cluster 3 was the "severe" cluster, characterized by older adults and patients with dyspnea or comorbidities (cardiovascular, diabetes, obesity). Cluster 4 included asymptomatic, pregnant, and less severe patients. We found differences in all clinical-epidemiologic characteristics according to the cluster to which they belonged.

CONCLUSION:

Using cluster analysis, we identified characteristic patterns in each group. Respiratory, gastrointestinal, dyspnea, anosmia, and ageusia symptoms were higher in the second COVID-19 wave than the first COVID-19 wave.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Aged / Female / Humans / Male / Pregnancy Country/Region as subject: South America / Peru Language: English Journal: Int J Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: J.ijid.2022.07.045

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Aged / Female / Humans / Male / Pregnancy Country/Region as subject: South America / Peru Language: English Journal: Int J Infect Dis Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: J.ijid.2022.07.045