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Neutrophil Extracellular Traps (NET) and SARS-CoV-2.
Pezeshki, Shaghayegh.
  • Pezeshki S; Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Immunopharmacol Immunotoxicol ; : 1-3, 2022 Oct 19.
Article in English | MEDLINE | ID: covidwho-2276354
ABSTRACT
NETosis is a type of neutrophil extinction that outcome in the liberation of extracellular chromatin and protein accumulation, which contains antiviral proteins, produced by an external pathogen. Neutrophils can show bipolar action in special circumstances. This event, along with other circumstances, involves COVID-19. Neutrophil extracellular traps (NETs) are involved in the pathogenesis of COVID-19 by creating a pro-inflammatory and pre-coagulation state that leads to numerous organ losses. This form of host defense, which is promoted by neutrophils, is closely related to the known cytokine storm in severe COVID-19 patients. Hence, these two elements reveal possibly the treatment of the target for SARS-CoV-2 infections intense.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: Immunopharmacol Immunotoxicol Journal subject: Allergy and Immunology / Pharmacology / Toxicology Year: 2022 Document Type: Article Affiliation country: 08923973.2022.2128368

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: Immunopharmacol Immunotoxicol Journal subject: Allergy and Immunology / Pharmacology / Toxicology Year: 2022 Document Type: Article Affiliation country: 08923973.2022.2128368