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Mesenteric Ischemia in Patients with Coronavirus 2019: A Scoping Review.
Gebran, Anthony; El Moheb, Mohamad; Argandykov, Dias; Mashbari, Hassan; Gartland, Rajshri M; Hwabejire, John O; Velmahos, George C; Kaafarani, Haytham M A.
  • Gebran A; Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • El Moheb M; Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Argandykov D; Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Mashbari H; Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Gartland RM; Department of Surgery, Faculty of Medicine, Jazan University, Saudi Arabia.
  • Hwabejire JO; Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Velmahos GC; Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Kaafarani HMA; Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Surg Infect (Larchmt) ; 23(9): 781-786, 2022 Nov.
Article in English | MEDLINE | ID: covidwho-2077582
ABSTRACT

Background:

Coronavirus 2019 (COVID-19) is a systemic disease associated with severe gastrointestinal complications including life-threatening mesenteric ischemia. We sought to review and summarize the currently available literature on the presentation, management, and outcomes of mesenteric ischemia in patients with COVID-19. Patients and

Methods:

The PubMed database was searched to identify studies published between January 2020 and January 2021 that reported one or more adult (≥18 years) patients with COVID-19 who developed mesenteric ischemia during hospitalization. The demographic characteristics, clinical and imaging findings, management, and outcomes of patients from each study were extracted and summarized.

Results:

A total of 35 articles reporting on 61 patients with COVID-19 with mesenteric ischemia met the eligibility and were included in our study. The mean age was 60 (±15.9) years, and 53% of patients were male. Imaging findings of these patients included mesenteric arterial or venous thromboembolism, followed by signs of mesenteric ischemia. Sixty-seven percent of patients were taken to the operating room for an exploratory laparotomy and bowel resection and 21% were managed conservatively. The terminal ileum was the most commonly involved area of necrosis (26%). The mortality rate of patients with COVID-19 with mesenteric ischemia was 33%, and the most common cause of death was multiorgan failure or refractory septic shock. Twenty-seven percent of patients managed operatively died during the post-operative period.

Conclusions:

Mesenteric ischemia in patients with COVID-19 is a devastating complication associated with a high rate of morbidity and mortality. Further efforts should focus on developing strategies for early recognition and management.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Digestive System Surgical Procedures / Mesenteric Ischemia / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study / Reviews Topics: Long Covid Limits: Adult / Female / Humans / Male / Middle aged Language: English Journal: Surg Infect (Larchmt) Journal subject: Bacteriology Year: 2022 Document Type: Article Affiliation country: Sur.2022.154

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Digestive System Surgical Procedures / Mesenteric Ischemia / COVID-19 Type of study: Diagnostic study / Observational study / Prognostic study / Reviews Topics: Long Covid Limits: Adult / Female / Humans / Male / Middle aged Language: English Journal: Surg Infect (Larchmt) Journal subject: Bacteriology Year: 2022 Document Type: Article Affiliation country: Sur.2022.154