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A Novel Development of Sarcoidosis Following COVID-19 Vaccination and a Literature Review.
Numakura, Tadahisa; Murakami, Koji; Tamada, Tsutomu; Yamaguchi, Chiaki; Inoue, Chihiro; Ohkouchi, Shinya; Tode, Naoki; Sano, Hirohito; Aizawa, Hiroyuki; Sato, Kei; Mitsune, Ayumi; Kurosawa, Hajime; Nakazawa, Toru; Sugiura, Hisatoshi.
  • Numakura T; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
  • Murakami K; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
  • Tamada T; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
  • Yamaguchi C; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Japan.
  • Inoue C; Department of Anatomic Pathology, Tohoku University Graduate School of Medicine, Japan.
  • Ohkouchi S; Department of Occupational Health, Tohoku University Graduate School of Medicine, Japan.
  • Tode N; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
  • Sano H; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
  • Aizawa H; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
  • Sato K; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
  • Mitsune A; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
  • Kurosawa H; Department of Occupational Health, Tohoku University Graduate School of Medicine, Japan.
  • Nakazawa T; Department of Ophthalmology, Tohoku University Graduate School of Medicine, Japan.
  • Sugiura H; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Japan.
Intern Med ; 61(20): 3101-3106, 2022 Oct 15.
Article in English | MEDLINE | ID: covidwho-2079920
ABSTRACT
BNT162b2 (Pfizer/BioNTech) is a coronavirus disease 2019 (COVID-19) vaccine containing nucleoside-modified messenger RNA encoding the severe acute respiratory syndrome coronavirus 2 spike glycoprotein. Recently, ocular complications of mRNA vaccines have been reported increasingly frequently. However, immunological adverse events due to mRNA vaccines in real-world settings are not fully known. We herein report the novel development of sarcoidosis manifested as uveitis, bilateral hilar lymphadenopathy, angiotensin-converting enzyme elevation, and epithelioid and giant cell granuloma formation in the lung soon after the first BNT162b2 injection and review the current literature, including three reported cases of sarcoid-like reaction following COVID-19 vaccination.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Sarcoidosis / COVID-19 Vaccines / COVID-19 Type of study: Case report / Observational study / Reviews Topics: Vaccines Limits: Humans Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2022 Document Type: Article Affiliation country: Internalmedicine.0104-22

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Sarcoidosis / COVID-19 Vaccines / COVID-19 Type of study: Case report / Observational study / Reviews Topics: Vaccines Limits: Humans Language: English Journal: Intern Med Journal subject: Internal Medicine Year: 2022 Document Type: Article Affiliation country: Internalmedicine.0104-22