Your browser doesn't support javascript.
Case Report: A 29-Year-Old Pregnant Woman at 24 Weeks of Gestation Presenting with Laryngotracheitis and COVID-19 Due to the R.1 Variant of SARS-CoV-2.
Tanaka, Yoshihito; Hirano, Kojiro; Sekino, Eriko; Shimane, Toshikazu; Kobayashi, Hitome.
  • Tanaka Y; Department of Otorhinolaryngology, Showa University School of Medicine, Tokyo, Japan.
  • Hirano K; Department of Otorhinolaryngology, Showa University School of Medicine, Tokyo, Japan.
  • Sekino E; Department of Otorhinolaryngology, Showa University School of Medicine, Tokyo, Japan.
  • Shimane T; Head and Neck Oncology Center, Showa University, Tokyo, Japan.
  • Kobayashi H; Department of Otorhinolaryngology, Showa University School of Medicine, Tokyo, Japan.
Am J Case Rep ; 23: e937834, 2022 Oct 18.
Article in English | MEDLINE | ID: covidwho-2080955
ABSTRACT
BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was discovered in December 2019 in Wuhan, China. Coronavirus disease (COVID-19) mainly presents with lower respiratory tract symptoms. On the other hand, laryngotracheitis or croup shows barky cough and it is rare in adults. There were no reports of laryngotracheitis with COVID-19 in pregnant women. We report the case of a pregnant woman at 24 weeks of gestation presenting with acute laryngotracheitis and COVID-19 due to the R.1 variant of SARS-CoV-2. CASE REPORT A 29-year-old previously healthy woman at 24 weeks of gestation presented with hoarseness and sore throat without fever, of 1-day duration. Although she was treated by her primary care physician with nebulized epinephrine, her symptoms did not resolve. She came to our hospital the same day. On arrival at our department, she was tachypneic and had a 95% oxygen saturation. She had stridor and barking cough. Laryngeal endoscopy revealed edema under the vocal cords. She was hospitalized urgently. SARS-CoV-2 polymerase chain reaction (PCR) testing was positive and the E484K mutation was confirmed. She was treated with oral and inhaled corticosteroids. Two days after admission, her symptoms were improved. She was discharged 10 days after admission. Edema under the vocal cords was completely improved 24 days after discharge. There were no adverse effects on the pregnancy. CONCLUSIONS COVID-19 laryngotracheitis has a more severe disease course than other causes, especially in pregnancy. COVID-19 laryngotracheitis should be use corticosteroids to treatment. Prednisolone is recommended for laryngotracheitis with COVID-19 during pregnancy.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Croup / COVID-19 Type of study: Case report / Prognostic study Topics: Variants Limits: Adult / Female / Humans / Pregnancy Language: English Journal: Am J Case Rep Year: 2022 Document Type: Article Affiliation country: AJCR.937834

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Croup / COVID-19 Type of study: Case report / Prognostic study Topics: Variants Limits: Adult / Female / Humans / Pregnancy Language: English Journal: Am J Case Rep Year: 2022 Document Type: Article Affiliation country: AJCR.937834