Link between COVID-19 vaccines and myocardial infarction.
World J Clin Cases
; 10(28): 10109-10119, 2022 Oct 06.
Article
in English
| MEDLINE | ID: covidwho-2288204
ABSTRACT
BACKGROUND:
Vaccines for coronavirus disease 2019 (COVID-19) include ChAdOx1-SARS-COV-2 (AstraZeneca), Ad26.COV2.S (Janssen), mRNA-1273 (Moderna), BNT162b2 (Pfizer), BBIBP-CorV (Sinopharm), CoronaVac (Sinovac), and Bharat Biotech BBV152 (Covaxin).AIM:
To find the association between COVID-19 vaccines and myocardial infarction (MI).METHODS:
This is a systematic review that involved searching databases such as MEDLINE, EMBASE, and PakMediNet after making a search strategy using MeSH and Emtree terms. Eligibility criteria were set, and studies having no mention of MI as a complication of COVID-19 vaccination, protocols, genetic studies, and animal studies were excluded. Data was extracted using a predesigned extraction table, and 29 studies were selected after screening and applying the eligibility criteria.RESULTS:
The majority of studies mentioned AstraZeneca (18 studies) followed by Pfizer (14 studies) and Moderna (9 studies) in subjects reporting MI after vaccination. Out of all the studies, 69% reported MI cases after the first COVID-19 vaccination dose and 14% after the second, 44% reported ST-segment elevation MI, and 26% reported non-ST-segment elevation MI. The mortality rate was 29% after MI.CONCLUSION:
In conclusion, many studies linked MI to COVID-19 vaccinations, but no definitive association could be found.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Reviews
/
Systematic review/Meta Analysis
Topics:
Vaccines
Language:
English
Journal:
World J Clin Cases
Year:
2022
Document Type:
Article
Affiliation country:
Wjcc.v10.i28.10109
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