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Advances in Biosensing Technologies for Diagnosis of COVID-19.
Alsalameh, Sulaiman; Alnajjar, Khalid; Makhzoum, Tariq; Al Eman, Noor; Shakir, Ismail; Mir, Tanveer Ahmad; Alkattan, Khaled; Chinnappan, Raja; Yaqinuddin, Ahmed.
  • Alsalameh S; College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia.
  • Alnajjar K; College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia.
  • Makhzoum T; College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia.
  • Al Eman N; College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia.
  • Shakir I; College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia.
  • Mir TA; Laboratory of Tissue/Organ Bioengineering and BioMEMS, Organ Transplant Centre of Excellence, Transplant Research and Innovation Department, King Faisal Specialist Hospital and Research Centre, Riyadh 11211, Saudi Arabia.
  • Alkattan K; College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia.
  • Chinnappan R; College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia.
  • Yaqinuddin A; College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia.
Biosensors (Basel) ; 12(10)2022 Oct 20.
Article in English | MEDLINE | ID: covidwho-2081840
ABSTRACT
The COVID-19 pandemic has severely impacted normal human life worldwide. Due to its rapid community spread and high mortality statistics, the development of prompt diagnostic tests for a massive number of samples is essential. Currently used traditional methods are often expensive, time-consuming, laboratory-based, and unable to handle a large number of specimens in resource-limited settings. Because of its high contagiousness, efficient identification of SARS-CoV-2 carriers is crucial. As the advantages of adopting biosensors for efficient diagnosis of COVID-19 increase, this narrative review summarizes the recent advances and the respective reasons to consider applying biosensors. Biosensors are the most sensitive, specific, rapid, user-friendly tools having the potential to deliver point-of-care diagnostics beyond traditional standards. This review provides a brief introduction to conventional methods used for COVID-19 diagnosis and summarizes their advantages and disadvantages. It also discusses the pathogenesis of COVID-19, potential diagnostic biomarkers, and rapid diagnosis using biosensor technology. The current advancements in biosensing technologies, from academic research to commercial achievements, have been emphasized in recent publications. We covered a wide range of topics, including biomarker detection, viral genomes, viral proteins, immune responses to infection, and other potential proinflammatory biomolecules. Major challenges and prospects for future application in point-of-care settings are also highlighted.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Biosensing Techniques / COVID-19 Type of study: Diagnostic study / Reviews Limits: Humans Language: English Year: 2022 Document Type: Article Affiliation country: Bios12100898

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Biosensing Techniques / COVID-19 Type of study: Diagnostic study / Reviews Limits: Humans Language: English Year: 2022 Document Type: Article Affiliation country: Bios12100898