Cutaneous manifestations of COVID-19: Report of three cases and a review of literature.
J Dermatol Sci
; 98(2): 75-81, 2020 May.
Article
in English
| MEDLINE | ID: covidwho-208374
ABSTRACT
BACKGROUND:
Various cutaneous manifestations have been observed in patients with COVID-19 infection. However, overall similarities in the clinical presentation of these dermatological manifestations have not yet been summarized.OBJECTIVE:
This review aims to provide an overview of various cutaneous manifestations in patients with COVID-19 through three case reports and a literature review.METHODS:
A literature search was conducted using PubMed, OVID, and Google search engines for original and review articles. Studies written in the English language that mentioned cutaneous symptoms and COVID-19 were included.RESULTS:
Eighteen articles and three additional cases reported in this paper were included in this review. Of these studies, 6 are case series and 12 are case report studies. The most common cutaneous manifestation of COVID-19 was found to be maculopapular exanthem (morbilliform), presenting in 36.1% (26/72) patients. The other cutaneous manifestations included a papulovesicular rash (34.7%, 25/72), urticaria (9.7%, 7/72), painful acral red purple papules (15.3%, 11/72) of patients, livedo reticularis lesions (2.8%, 2/72) and petechiae (1.4%, 1/72). Majority of lesions were localized on the trunk (66.7%, 50/72), however, 19.4% (14/72) of patients experienced cutaneous manifestations in the hands and feet. Skin lesion development occurred before the onset of respiratory symptoms or COVID-19 diagnosis in 12.5% (9/72) of the patients, and lesions spontaneously healed in all patients within 10 days. Majority of the studies reported no correlation between COVID-19 severity and skin lesions.CONCLUSION:
Infection with COVID-19 may result in dermatological manifestations with various clinical presentations, which may aid in the timely diagnosis of this infection.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Skin
/
Skin Diseases, Viral
/
Coronavirus Infections
/
Betacoronavirus
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
/
Reviews
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
J Dermatol Sci
Journal subject:
Dermatology
Year:
2020
Document Type:
Article
Affiliation country:
J.jdermsci.2020.04.011
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