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A pilot surveillance report of SARS-CoV-2 rapid antigen test results among volunteers in Germany, 1st week of July 2022.
Stemler, Jannik; Salmanton-García, Jon; Weise, Ben; Többen, Christina; Joisten, Carolin; Fleig, Julian; Cornely, Oliver A.
  • Stemler J; Faculty of Medicine and University Hospital Cologne, Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Herderstr. 52-54, 50931, Cologne, Germany. Jannik.Stemler@uk-koeln.de.
  • Salmanton-García J; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany. Jannik.Stemler@uk-koeln.de.
  • Weise B; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany. Jannik.Stemler@uk-koeln.de.
  • Többen C; Faculty of Medicine and University Hospital Cologne, Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Herderstr. 52-54, 50931, Cologne, Germany.
  • Joisten C; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany.
  • Fleig J; Faculty of Medicine and University Hospital Cologne, Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Herderstr. 52-54, 50931, Cologne, Germany.
  • Cornely OA; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD) and Excellence Center for Medical Mycology (ECMM), University of Cologne, Cologne, Germany.
Infection ; 2022 Oct 24.
Article in English | MEDLINE | ID: covidwho-2282527
ABSTRACT

PURPOSE:

We hypothesized that SARS-CoV-2 infection numbers reported by governmental institutions are underestimated due to high dark figures as only results from polymerase chain reaction (PCR) tests are incorporated in governmental statistics and testing capacities were further restricted as of July, 2022.

METHODS:

A point prevalence investigation was piloted by rapid antigen testing (RAT) among participants of the VACCELERATE volunteer registry. 2400 volunteers were contacted, of which 500 received a RAT including instructions for self-testing in the first week of July, 2022. Results were self-reported via e-mail.

RESULTS:

419 valid RAT results were collected until July 7th, 2022. Between July-1 and July-7, 2022, 7/419 (1.67%) tests were positive. Compared to reports of the German Federal Government, our results suggest a more than twofold higher prevalence. Three out of seven positive individuals did not have a PCR test and are therefore likely not to be displayed in governmental statistics.

CONCLUSION:

Our findings imply that the actual prevalence of SARS-CoV-2 may be higher than detected by current surveillance systems, so that current pandemic surveillance and testing strategies may be adapted.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study Language: English Year: 2022 Document Type: Article Affiliation country: S15010-022-01931-7

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study Language: English Year: 2022 Document Type: Article Affiliation country: S15010-022-01931-7