Chapter 6 - Terpenes, meroterpenoids, and artemisinin and SARS-CoV-2

ABSTRACT

The coronavirus disease-2019 (COVID-19) pandemic is caused by a novel coronavirus;the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Millions of cases and deaths to date have resulted in a global challenge for healthcare systems. There are currently no effective therapeutic approaches for the prevention and treatment of COVID-19. Therefore, the identification of effective therapeutics is a necessity. Terpenes, meroterpenoids, and artemisinin are natural products that could serve as a source of new drugs or as prototypes to develop effective pharmacotherapeutic agents. This chapter deals with the biological properties and nutraceutical application of terpenes, meroterpenoids, and artemisinin and also finds out the possible interaction and discusses the mechanism of action of these natural products against SARs-CoV-2. The information reviewed here might provide useful clues and lay the foundation for developing new terpenes, meroterpenoid, and artemisinin-derived drugs.